1-((2-methylallyl)oxy)hexane | 854256-14-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-((2-methylallyl)oxy)hexane
• 英文别名: hexyl-methallyl ether；2-Methyl-propen-(1)-ol-(3)-hexylaether；3-Hexyloxy-2-methyl-propen-(1)；Hexyl-methallyl-aether；1-(2-methyl-allyloxy)-hexane；1-(2-methylprop-2-enoxy)hexane
• CAS: 854256-14-7
• 化学式: C₁₀H₂₀O
• 分子量: 156.268
• InChiKey: ZNFGHVDQZWPWQP-UHFFFAOYSA-N

物化性质

• 沸点：
  189.9±9.0 °C(Predicted)
• 密度：
  0.801±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-((2-methylallyl)oxy)hexane 在 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 正戊烷 为溶剂， 以100%的产率得到1-((2-methylprop-1-en-1-yl)oxy)hexane
  参考文献：
  名称：

  Isomerization of Allyl Ethers Initiated by Lithium Diisopropylamide

  摘要：

  Lithium diisopropylamide (LDA) promotes virtually quantitative conversion of allylic ethers to (Z)-propenyl ethers. It was discovered that allylic ethers can be isomerized efficiently with very high stereoselectivity to (Z)-propenyl ethers by LDA in THF at room temperature. The reaction time for the conversion increases with more sterically hindered allylic ethers. Different amides were also compared with LDA for their ability to effect this isomerization.

  DOI：

  10.1021/ol102029u
• 作为产物：
  描述：

  3-氯-2-甲基丙烯 、 正己醇 在 四丁基氢氧化铵 sodium hydroxide 作用下， 以 水 为溶剂， 反应 10.0h， 以72%的产率得到1-((2-methylallyl)oxy)hexane
  参考文献：
  名称：

  Aldehyde Compositions and Methods for Providing Fragrance Containing the Same

  摘要：

  本发明涉及一种新型醛化合物，其通式如下所示：其中R是由3到10个碳原子组成的直链、支链烃基，可能含有一个或多个氧杂原子。

  公开号：

  US20080319088A1

文献信息

• Aldehyde compositions and methods for providing fragrance containing the same
  申请人：International Flavors & Fragrances Inc.

  公开号：US07932293B2

  公开（公告）日：2011-04-26

  The present invention is directed to the novel aldehyde compounds, represented by the general structure of Formula I set forth below: wherein R is a straight, branched hydrocarbon moiety consisting of 3 to 10 carbon atoms and may contain one or more oxygen heteroatom.

  本发明涉及一种新型醛化合物，其通式如下所示：其中R是由3至10个碳原子组成的直链、支链烃基，可能含有一个或多个氧杂原子。
• Reaction products of 2-methyl-1, 3-dichloropropane and alcohols
  申请人：DOW CHEMICAL CO

  公开号：US02148437A1

  公开（公告）日：1939-02-28
• Controlled Radical Polymerization-Derived Block Copolymer Compositions for Medical Device Coatings
  申请人：Chen Mingfei

  公开号：US20080305143A1

  公开（公告）日：2008-12-11

  Controlled radical polymerization-derived biocompatible block copolymer coatings for medical devices are disclosed. Specifically, block copolymer coatings designed to control the release of bioactive agents from medical devices in vivo are disclosed. The present application also discloses providing vascular stents with drug-eluting controlled release block copolymer coatings and related methods for making these medical devices and coatings.
• US7932293B2
  申请人：——

  公开号：US7932293B2

  公开（公告）日：2011-04-26
• [EN] AMINOALCOHOL LIPIDOIDS AND USES THEREOF<br/>[FR] LIPIDOÏDES AMINOALCOOL ET LEURS UTILISATIONS
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2010053572A2

  公开（公告）日：2010-05-14

  Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.