3-[(4-acetylphenyl)thio]-propanoic acid methyl ester | 1153277-69-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-[(4-acetylphenyl)thio]-propanoic acid methyl ester
• 英文别名: Methyl 3-(4-acetylphenyl)sulfanylpropanoate
• CAS: 1153277-69-0
• 化学式: C₁₂H₁₄O₃S
• mdl: MFCD12144604
• 分子量: 238.307
• InChiKey: OAQJOWGSXAKWQD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  68.7
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-[(4-acetylphenyl)thio]-propanoic acid methyl ester 在 间氯过氧苯甲酸 、 三氟乙酸 作用下， 以 二氯甲烷 、 氘代乙腈 为溶剂， 反应 3.5h， 生成
  参考文献：
  名称：

  Synthesis and structural features of sulfur-substituted calix[4]pyrrole for a bottom-up control of the substrate-directed self-assembly of supramolecular structures

  摘要：

  The synthesis of six new calix[4]pyrroles, containing sulfur-substituted phenylene units is reported. Halogen-anions and organic aromatic mono- and bis-anions have been selected to explore the formation of host-guest complexes and the possible self-assembly of multi-component structures with the six calixpyrroles. The type of aryl substitution modulates the strength of binding and the selectivity towards different anions and, in some cases, the combination of receptors and bis-anionic precursors, offers a way to build systems in which capsular assemblies are observed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.07.082
• 作为产物：
  描述：

  4'-巯基苯乙酮 、 丙烯酸甲酯（MA） 在 苄基三甲基氢氧化铵 作用下， 以 四氢呋喃 、 甲醇 为溶剂， 以95%的产率得到3-[(4-acetylphenyl)thio]-propanoic acid methyl ester
  参考文献：
  名称：

  Synthesis and structural features of sulfur-substituted calix[4]pyrrole for a bottom-up control of the substrate-directed self-assembly of supramolecular structures

  摘要：

  The synthesis of six new calix[4]pyrroles, containing sulfur-substituted phenylene units is reported. Halogen-anions and organic aromatic mono- and bis-anions have been selected to explore the formation of host-guest complexes and the possible self-assembly of multi-component structures with the six calixpyrroles. The type of aryl substitution modulates the strength of binding and the selectivity towards different anions and, in some cases, the combination of receptors and bis-anionic precursors, offers a way to build systems in which capsular assemblies are observed. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2011.07.082

文献信息

• A Strategy for the Synthesis of Sulfonamides on DNA
  作者：Wei Liu、Wei Deng、Saisai Sun、Chunyan Yu、Xubo Su、Aliang Wu、Youlang Yuan、Zhonglin Ma、Ke Li、Hongfang Yang、Xuanjia Peng、Justin Dietrich

  DOI：10.1021/acs.orglett.9b03843

  日期：2019.12.20

  An efficient method is reported to synthesize sulfonamides on DNA from sulfinic acids or sodium sulfinates and amines in the presence of iodine under mild conditions. This method demonstrates a major expansion of scope of sulfonamide formation on DNA through the utilization of a novel sodium carbonate-sodium sulfinate bifunctional reagent class.

  据报道，一种有效的方法是在温和条件下，在碘的存在下，由亚磺酸或亚磺酸钠和胺在DNA上合成磺酰胺。该方法证明了通过利用新型碳酸钠-亚磺酸钠双功能试剂类别在DNA上形成磺酰胺的范围有了很大的扩展。
• Modulating the Surface and Photophysical Properties of Carbon Dots to Access Colloidal Photocatalysts for Cross-Couplings
  作者：Zhouxiang Zhao、Bartholomäus Pieber、Martina Delbianco

  DOI：10.1021/acscatal.2c04025

  日期：2022.11.18

  are generally photocatalyzed by noble metal complexes. Low-cost and easy-to-prepare carbon dots (CDs) are attractive quasi-homogeneous photocatalyst alternatives, but their applicability is limited by their short photoluminescence (PL) lifetimes. By tuning the surface and PL properties of CDs, we designed colloidal CD nano-photocatalysts for a broad range of Ni-mediated cross-couplings between aryl

  光氧化还原介导的镍催化交叉偶联是形成碳-杂原子键的强大转化，通常由贵金属络合物光催化。低成本且易于制备的碳点 (CD) 是极具吸引力的准均相光催化剂替代品，但它们的适用性受到光致发光 (PL) 寿命短的限制。通过调整 CD 的表面和 PL 特性，我们设计了胶体 CD 纳米光催化剂，用于芳基卤化物和亲核试剂之间广泛的 Ni 介导的交叉偶联。特别是，装饰有氨基的 CD 允许在温和、无碱的条件下与各种芳基卤化物和硫醇偶联。机理研究表明 Ni 助催化剂对 CD 激发态进行了动态猝灭，并确定了碘化吡啶 (pyHI)，
• Synthesis and structural features of sulfur-substituted calix[4]pyrrole for a bottom-up control of the substrate-directed self-assembly of supramolecular structures
  作者：Anna Barattucci、Paola Bonaccorsi、Grazia Cafeo、Franz H. Kohnke、Teresa Papalia

  DOI：10.1016/j.tet.2011.07.082

  日期：2011.9

  The synthesis of six new calix[4]pyrroles, containing sulfur-substituted phenylene units is reported. Halogen-anions and organic aromatic mono- and bis-anions have been selected to explore the formation of host-guest complexes and the possible self-assembly of multi-component structures with the six calixpyrroles. The type of aryl substitution modulates the strength of binding and the selectivity towards different anions and, in some cases, the combination of receptors and bis-anionic precursors, offers a way to build systems in which capsular assemblies are observed. (C) 2011 Elsevier Ltd. All rights reserved.