4-(1-methyl-1-phenylethyl)-quinaldine | 1262098-85-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 4-(1-methyl-1-phenylethyl)-quinaldine
• 英文别名: 2-Methyl-4-(2-phenylpropan-2-yl)quinoline；2-methyl-4-(2-phenylpropan-2-yl)quinoline
• CAS: 1262098-85-0
• 化学式: C₁₉H₁₉N
• 分子量: 261.367
• InChiKey: DTHRZSAMPIVHIC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  2-甲基喹啉 、 异丙苯 在 双氧水 、 对甲苯磺酸 作用下， 以 水 、 乙腈 为溶剂， 反应 16.0h， 以6%的产率得到4-(1-methyl-1-phenylethyl)-quinaldine
  参考文献：
  名称：

  Reactivity of benzyl radicals: The trapping of primary, secondary and tertiary benzyl radicals with heterocyclic bases

  摘要：

  A photochemical benzylation of protonated quinolines was realized by single electron transfer (SET) to the excited state of the quinoline from the aromatic reactant. The benzylated product is formed by cross-coupling between the benzyl radical and the heterocyclic radical when they are in close proximity to one another. This allows the formation of products which are, to the best of our knowledge, unaccessible in other ways and which have now been obtained for the first time. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jphotochem.2010.05.026

文献信息

• Reactivity of benzyl radicals: The trapping of primary, secondary and tertiary benzyl radicals with heterocyclic bases
  作者：Luigi Brivio、Tullio Caronna、Francesca Fontana、Cristian Gambarotti、Andrea Mele、Isabella Natali Sora、Carlo Punta、Francesco Recupero

  DOI：10.1016/j.jphotochem.2010.05.026

  日期：2010.7

  A photochemical benzylation of protonated quinolines was realized by single electron transfer (SET) to the excited state of the quinoline from the aromatic reactant. The benzylated product is formed by cross-coupling between the benzyl radical and the heterocyclic radical when they are in close proximity to one another. This allows the formation of products which are, to the best of our knowledge, unaccessible in other ways and which have now been obtained for the first time. (C) 2010 Elsevier B.V. All rights reserved.