dimethyl 3-(4-nitrophenyl)-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate | 1433876-61-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: dimethyl 3-(4-nitrophenyl)-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate
• 英文别名: Dimethyl 3-(4-nitrophenyl)-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate
• CAS: 1433876-61-9
• 化学式: C₂₃H₁₈N₂O₆
• 分子量: 418.406
• InChiKey: PPGHLIPZYRKDMF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  110
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  对硝基苯甲醛 、 2-萘胺 、 丁炔二酸二甲酯 在 三氯化锑 作用下， 以 乙腈 为溶剂， 反应 6.0h， 以77%的产率得到dimethyl 3-(4-nitrophenyl)-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate
  参考文献：
  名称：

  One pot imino Diels–Alder reaction for the synthesis of 3-aryl-3,4-dihydrobenzo[f]quinoline derivatives catalyzed by antimony trichloride

  摘要：

  An one pot simple and efficient approach toward the synthesis of dialkyl-3-aryl-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate and its dehydro derivatives have been developed through the three-component reaction of aromatic aldehydes, 2-naphthylamine, and but-2-ynedioate catalyzed by SbCl3 under reflux in acetonitrile in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.03.093

文献信息

• One pot imino Diels–Alder reaction for the synthesis of 3-aryl-3,4-dihydrobenzo[f]quinoline derivatives catalyzed by antimony trichloride
  作者：Gourhari Maiti、Rajiv Karmakar、Utpal Kayal

  DOI：10.1016/j.tetlet.2013.03.093

  日期：2013.6

  An one pot simple and efficient approach toward the synthesis of dialkyl-3-aryl-3,4-dihydrobenzo[f]quinoline-1,2-dicarboxylate and its dehydro derivatives have been developed through the three-component reaction of aromatic aldehydes, 2-naphthylamine, and but-2-ynedioate catalyzed by SbCl3 under reflux in acetonitrile in good to excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.