3-benzoylpyrrolidine-2,5-dione | 19646-23-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3-benzoylpyrrolidine-2,5-dione
• 英文别名: 3-Benzoyl-succinimid
• CAS: 19646-23-2
• 化学式: C₁₁H₉NO₃
• 分子量: 203.197
• InChiKey: XOPJKILAVGOQJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  63.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  马来酰亚胺 、 苯甲醛 在 3-mesityl-5,6,7,8-tetrahydro-4H-cyclohepta[d]thiazol-3-ium perchlorate 、 potassium carbonate 作用下， 以 四氢呋喃 为溶剂， 反应 0.5h， 以76%的产率得到3-benzoylpyrrolidine-2,5-dione
  参考文献：
  名称：

  Isa‒NHC‒催化的芳香醛与马来酰亚胺的分子间Stetter反应：有效获得3‒aroylsuccinimides

  摘要：

  使用噻唑基亚烷基盐衍生的Isa‒NHC作为有效的有机催化剂，已开发出芳香族醛与马来酰亚胺的分子间Stetter反应。合成的Stetter产品“ 3‒芳酰基琥珀酰亚胺”是合成天然产物和生物活性化合物的重要组成部分。反应条件温和，并且容许芳族醛和马来酰亚胺氮上的各种取代基。

  DOI：

  10.1016/j.tet.2018.03.009

文献信息

• A convenient diastereoselective total synthesis of andrimid
  作者：AV Rama Rao、A.K. Singh、Ch.V.N.S. Varaprasad

  DOI：10.1016/s0040-4039(00)92179-8

  日期：1991.1

  A convenient diastereoselective synthesis of andrimid was accomplished in a straightforward approach and also several β-substituted cyclic imides were prepared in a facile manner.

  以简单的方法完成了对芳族化合物的便利的非对映选择性合成，并且还以简便的方式制备了几种β-取代的环酰亚胺。
• Mulls containing chain structure clay suspension aids
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0034387A2

  公开（公告）日：1981-08-26

  A liquid mull is provided having improved physical stability, consisting of a liquid phase, comprising a major proportion of a nonionic surfactant and optionally a minor proportion of a nonaqueous solvent, and a dispersed solid phase comprising a particulate material which is insoluble in the liquid phase of the mull. From 1 % to 15% by weight of the composition of a chain structure type clay is included to aid the physical stability of the mull, so that insoluble particulate materials such as builders having ordinary particle sizes may also be incorporated. Preferred compositions are substantially anhydrous to allowthe optional inclusion of water sensi. tive detergency adjuvants such as enzymes or bleaches. The compositions may optionally contain up to 25% of a further dispersion aid selected from anionic surfactants, cationic surfactants, zwitterionic surfactants and hydrotropic materials. Such mulls have utility, for example, as detergent compositions.

  本发明提供了一种具有更好物理稳定性的液体闷闷不乐剂，它由液相和分散固相组成，液相主要由非离子表面活性剂和少量非水溶剂组成，分散固相由不溶于闷闷不乐剂液相的颗粒材料组成。按重量计，在组合物中加入 1%至 15%的链状结构粘土，以提高泥浆的物理稳定性，这样也可以加入不溶于泥浆的颗粒材料，如具有普通粒度的建筑材料。优选的组合物基本上是无水的，这样就可以选择性地加入对水敏感的去污佐剂，如酶或漂白剂。组合物还可以选择性地含有高达 25% 的其它分散助剂，这些助剂选自阴离子表面活性剂、阳离子表面活性剂、齐聚亚铵盐表面活性剂和亲水材料。例如，这种混合物可用作洗涤剂组合物。
• Detergent compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0063017A1

  公开（公告）日：1982-10-20

  Granular detergent compositions comprising organic surfactant, phosphate detergency builder wherein at least 6% of the builder consists of a mixture of water-soluble orthophosphate and pyrophosphate salts, organic peroxyacid bleach precursor and specified polymeric polycarboxylic acids or salts thereof. The compositions provide improved low temperature cleaning together with excellent soil deposition and whiteness maintenance performance.

  颗粒状洗涤剂组合物由有机表面活性剂、磷酸盐去污增效剂（其中至少 6% 的增效剂由水溶性正磷酸盐和焦磷酸盐的混合物组成）、有机过氧酸漂白剂前体和特定的聚合聚羧酸或其盐组成。这种组合物不仅能改善低温清洁效果，还具有出色的污垢沉积和白度保持性能。
• Detergent additive compositions and preparations and use thereof in detergent compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0062523A2

  公开（公告）日：1982-10-13

  A detergent additive composition in the form of an extrudate comprising 75% to 95% of particulate infusible solids comprising storage-sensitive detergent-additive material and 5 to 25% of ethoxylated nonionic surfactant The storage-sensitive detergent additive material is preferably an organic peroxy acid bleach precursor. When added to detergent compositions, the additive compositions have excellent storage stability and water-dispersibility characteristics.

  一种以挤出物形式存在的洗涤剂添加剂组合物，其 75% 至 95% 的可浸润微粒固体由对储存敏感的洗涤剂添加剂材料和 5% 至 25% 的乙氧基化非离子表面活性剂组成。添加到洗涤剂组合物中后，添加剂组合物具有优异的储存稳定性和水分散性。
• Granular laundry compositions
  申请人：THE PROCTER & GAMBLE COMPANY

  公开号：EP0028432B1

  公开（公告）日：1984-01-18