Ziziphin

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: Ziziphin
• 英文别名: [(2S,3R,4R,5S,6S)-3-acetyloxy-2-[[(1S,2R,5R,7S,10R,11R,14R,15S,16S,18R,20S)-7-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-2,6,6,10,16-pentamethyl-18-(2-methylprop-1-enyl)-19,21-dioxahexacyclo[18.2.1.01,14.02,11.05,10.015,20]tricosan-16-yl]oxy]-5-hydroxy-6-methyloxan-4-yl] acetate
• 化学式: C₅₁H₈₀O₁₈
• 分子量: 981.2
• InChiKey: SPFBVQWRJFUDBB-FYBFSNJASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  69
• 可旋转键数：
  11
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  248
• 氢给体数：
  6
• 氢受体数：
  18

文献信息

• [EN] HIGH-PURITY STEVIOL GLYCOSIDES<br/>[FR] GLYCOSIDES DE STÉVIOL DE HAUTE PURETÉ
  申请人：PURECIRCLE SDN BHD

  公开号：WO2016043926A1

  公开（公告）日：2016-03-24

  Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2, reb M2, and reb I are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

  描述了制备高度纯化的蒸馏甘甜苷，特别是蒸甘甜苷A、D和M的方法。这些方法包括利用重组微生物将各种原始成分转化为目标蒸甘甜苷。此外，还披露了新型蒸甘甜苷reb D2、reb M2和reb I，以及它们的制备方法。这些高度纯化的蒸甜苷可作为无热量甜味剂，用于食用和可咀嚼的产品，如任何饮料、糖果、烘焙产品、饼干和口香糖。
• [EN] HIGH-PURITY STEVIOL GLYCOSIDES<br/>[FR] GLYCOSIDES DE STÉVIOL DE GRANDE PURETÉ
  申请人：PURECIRCLE SDN BHD

  公开号：WO2014193888A1

  公开（公告）日：2014-12-04

  Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

  描述了制备高度纯化的甜菊糖苷方法，特别是A、D和M型再黄甜菊苷。这些方法包括利用重组微生物将不同的起始成分转化为目标甜菊糖苷。此外，还披露了新型甜菊糖苷reb D2和reb M2，以及其制备方法。这些高度纯化的再黄甜菊苷可用作无热量甜味剂，用于可食用和可咀嚼的组合物，如任何饮料、糖果、烘焙产品、饼干和口香糖。
• Triterpene compositions and methods for use thereof
  申请人：Research Development Foundation

  公开号：US20030039705A1

  公开（公告）日：2003-02-27

  The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells. The present application is a continuation-in-part of co-pending U.S. Patent Application Ser. No. 60/099,066, filed Sep. 3, 1998, and a continuation-in-part of U.S. patent application Ser. No. 60/085,997, filed May 19, 1998. The entire text of each of the above-referenced disclosures is specifically incorporated by reference herein without disclaimer.

  本发明提供了从维多利亚金合欢(Acacia victoriae)物种中分离出来的新型皂苷混合物和化合物，以及它们的使用方法。这些化合物可能包含三萜基团，如金合欢酸或齐墩果酸，附着有寡糖和单萜基团。这些混合物和化合物具有与细胞凋亡和细胞毒性调节相关的特性，并对多种肿瘤细胞表现出强效的抗肿瘤作用。本申请是待决美国专利申请号60/099,066的续篇，该专利申请于1998年9月3日提交，并且是待决美国专利申请号60/085,997的续篇，该专利申请于1998年5月19日提交。上述所有引用文件的全部内容都被明确地并入本文，不做免责声明。
• HIGH-PURITY STEVIOL GLYCOSIDES
  申请人：Purecircle SDN BHD

  公开号：US20140357588A1

  公开（公告）日：2014-12-04

  Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

  本文描述了制备高度纯化的甜菊糖苷，特别是A、D和M型的方法。这些方法包括利用重组微生物将各种起始组分转化为目标甜菊糖苷。此外，还公开了新型甜菊糖苷reb D2和reb M2的方法。高度纯化的甜菊糖苷可用作无热量甜味剂，添加在食品和可咀嚼的组合物中，如任何饮料、糖果、烘焙产品、饼干和口香糖中。
• High-Purity Steviol Glycosides
  申请人：PURECIRCLE SDN BHD

  公开号：US20160198748A1

  公开（公告）日：2016-07-14

  Methods of preparing highly purified steviol glycosides, particularly rebaudiosides A, D and M are described. The methods include utilizing recombinant microorganisms for converting various staring compositions to target steviol glycosides. In addition, novel steviol glycosides reb D2 and reb M2 are disclosed, as are methods of preparing the same. The highly purified rebaudiosides are useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakery products, cookies, and chewing gums.

  本文描述了制备高度纯化的甜菊糖苷，特别是A、D和M型的方法。这些方法包括利用重组微生物将各种起始组成物转化为目标甜菊糖苷。此外，还披露了新型甜菊糖苷reb D2和reb M2，以及制备它们的方法。这些高度纯化的甜菊糖苷可用作无热量甜味剂，添加到各种食品和咀嚼物中，如饮料、糖果、烘焙产品、饼干和口香糖等。