(1R,2R,5R,6S,8S,11R)-6-hydroxy-6,12-dimethyl-14-oxapentacyclo[10.3.3.15,8.01,11.02,8]nonadecan-15-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,2R,5R,6S,8S,11R)-6-hydroxy-6,12-dimethyl-14-oxapentacyclo[10.3.3.15,8.01,11.02,8]nonadecan-15-one
• 化学式: C₂₀H₃₀O₃
• 分子量: 318.4
• InChiKey: WAZWEQYFSTXTHA-KDUBGUPVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  23
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Antimicrobial compositions and methods of using same
  申请人：CROWPIERCE TECHNOLOGIES, LLC

  公开号：US11246312B2

  公开（公告）日：2022-02-15

  Disclosed herein are antimicrobial compositions that are substantially odorless. The antimicrobial compositions can comprise, for example, a first essential oil and a second essential oil, wherein the composition is substantially odorless. In some examples, the composition can further comprise a third essential oil. The compositions described herein can, for example, reduce the population of microbes, such as Staphylococcus aureus or Escherichia coli, by 5 log or more. Also disclosed herein are beverages and food products including the compositions disclosed herein. Also disclosed herein is milk including the compositions disclosed herein. Also disclosed herein are methods for treating or preventing a microbial infection in a subject, the methods comprising administering to the subject an effective amount of any of the compositions disclosed herein. Also disclosed herein are methods for combating bovine mastitis, the methods comprising applying any of the compositions disclosed herein to cow udders.

  本文公开了基本无味的抗菌组合物。例如，抗菌组合物可以包括第一种精油和第二种精油，其中组合物基本上是无味的。在某些例子中，组合物还可以进一步包含第三种精油。例如，本文所述的组合物可以将金黄色葡萄球菌或大肠杆菌等微生物的数量减少 5 log 或更多。本文还公开了包括本文公开的组合物的饮料和食品。本文还公开了包括本文公开的组合物的牛奶。本文还公开了用于治疗或预防受试者微生物感染的方法，该方法包括向受试者施用有效量的本文公开的任何组合物。本文还公开了防治牛乳腺炎的方法，该方法包括将本文公开的任何组合物施用到牛乳房中。
• TOPICAL COMPOSITIONS AND METHODS OF USING THEREOF
  申请人：Ohio State Innovation Foundation

  公开号：EP3490569A1

  公开（公告）日：2019-06-05
• ANTIMICROBIAL COMPOSITIONS AND METHODS OF USING SAME
  申请人：GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.

  公开号：US20190343894A1

  公开（公告）日：2019-11-14

  Disclosed herein are antimicrobial compositions that are substantially odorless. The antimicrobial compositions can comprise, for example, a first essential oil and a second essential oil, wherein the composition is substantially odorless. In some examples, the composition can further comprise a third essential oil. The compositions described herein can, for example, reduce the population of microbes, such as Staphylococcus aureus or Escherichia coli , by 5 log or more. Also disclosed herein are beverages and food products including the compositions disclosed herein. Also disclosed herein is milk including the compositions disclosed herein. Also disclosed herein are methods for treating or preventing a microbial infection in a subject, the methods comprising administering to the subject an effective amount of any of the compositions disclosed herein. Also disclosed herein are methods for combating bovine mastitis, the methods comprising applying any of the compositions disclosed herein to cow udders.
• [EN] TOPICAL COMPOSITIONS AND METHODS OF USING THEREOF<br/>[FR] COMPOSITIONS TOPIQUES ET SES PROCÉDÉS D'UTILISATION
  申请人：OHIO STATE INNOVATION FOUNDATION

  公开号：WO2018023128A1

  公开（公告）日：2018-02-01

  Disclosed herein are topical compositions for the administration of active agents. The compositions can comprise zeolite nanoparticles dispersed in a topically acceptable carrier. The zeolite nanoparticles can further comprise an effective amount of an active agent adsorbed on the zeolite nanoparticles, encapsulated within the zeolite nanoparticles, or a combination thereof. Also provided sunscreen agents and antimicrobial agents, as well as compositions comprising sunscreen agents and antimicrobial agents.
• [EN] ANTIMICROBIAL COMPOSITIONS AND METHODS OF USING SAME<br/>[FR] COMPOSITIONS ANTIMICROBIENNES ET PROCÉDÉS D'UTILISATION DE CELLES-CI
  申请人：UNIV GEORGIA STATE RES FOUND

  公开号：WO2018129233A1

  公开（公告）日：2018-07-12

  Disclosed herein are antimicrobial compositions that are substantially odorless. The antimicrobial compositions can comprise, for example, a first essential oil and a second essential oil, wherein the composition is substantially odorless. In some examples, the composition can further comprise a third essential oil. The compositions described herein can, for example, reduce the population of microbes, such as Staphylococcus aureus or Escherichia coli, by 5 log or more. Also disclosed herein are beverages and food products including the compositions disclosed herein. Also disclosed herein is milk including the compositions disclosed herein. Also disclosed herein are methods for treating or preventing a microbial infection in a subject, the methods comprising administering to the subject an effective amount of any of the compositions disclosed herein. Also disclosed herein are methods for combating bovine mastitis, the methods comprising applying any of the compositions disclosed herein to cow udders.