(1R,2R,4aS,6aS,6bR,11R,12aR)-1,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-3,4,5,6,6a,7,8,8a,11,12,13,14b-dodecahydro-2H-picene-4a-carboxylic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (1R,2R,4aS,6aS,6bR,11R,12aR)-1,11-dihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-3,4,5,6,6a,7,8,8a,11,12,13,14b-dodecahydro-2H-picene-4a-carboxylic acid
• 化学式: C₃₀H₄₆O₅
• 分子量: 486.7
• InChiKey: LJORXTIGOHMBOS-IHJFDKSJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  35
• 可旋转键数：
  1
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  94.8
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• Ursolic acid for inhibiting muscle atrophy
  申请人：University of Iowa Research Foundation

  公开号：EP2571354B1

  公开（公告）日：2020-07-08
• METHODS FOR INHIBITING MUSCLE ATROPHY
  申请人：Adams Christopher M.

  公开号：US20130203712A1

  公开（公告）日：2013-08-08

  In one aspect, the invention relates methods for inhibiting or preventing muscle atrophy or increasing muscle mass by providing to a subject in need thereof an effective amount of ursolic acid, a derivative thereof, or an analog of the ursane scaffold. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• [EN] METHODS FOR INHIBITING MUSCLE ATROPHY<br/>[FR] PROCÉDÉS D'INHIBITION DE L'ATROPHIE MUSCULAIRE
  申请人：UNIV IOWA RES FOUND

  公开号：WO2011146768A1

  公开（公告）日：2011-11-24

  In one aspect, the invention relates methods for inhibiting or preventing muscle atrophy or increasing muscle mass by providing to a subject in need thereof an effective amount of ursolic acid, a derivative thereof, or an analog of the ursane scaffold. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.