19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al
• 英文别名: Potamogetonyde；[(1R,4aR,5R,8aR)-4a-formyl-5-[2-(furan-3-yl)ethyl]-1-methyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methyl acetate
• 化学式: C₂₂H₃₀O₄
• 分子量: 358.478
• InChiKey: OPDQOKREXYCJHD-YUMYIRISSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  26
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al 在 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 19,20-dihydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatriene
  参考文献：
  名称：

  Antialgal furano-diterpenes from Potamogeton natans L.

  摘要：

  Six furano-ent-labdanes, 19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-20,19-olide, 12(S)-hydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20,19-olide, 10 alpha ,19-dihydroxy-15,16-epoxy-8(17), 13(16),14-nor-ent-labdatriene, 19,20-dihydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatriene, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-19,20-olide, were isolated, together with the known potamogetonin, from the aquatic plant Potamogeton natans. Their structures were determined on the basis of their chemical and spectral data. The compounds showed in vitro phytotoxicity against Raphidocelis subcapitata, a microalga used in aquatic tests. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0031-9422(01)00203-5

文献信息

• Antialgal furano-diterpenes from Potamogeton natans L.
  作者：Marina DellaGreca、Antonio Fiorentino、Marina Isidori、Pietro Monaco、Fabio Temussi、Armando Zarrelli

  DOI：10.1016/s0031-9422(01)00203-5

  日期：2001.9

  Six furano-ent-labdanes, 19-acetoxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20-al, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-20,19-olide, 12(S)-hydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatrien-20,19-olide, 10 alpha ,19-dihydroxy-15,16-epoxy-8(17), 13(16),14-nor-ent-labdatriene, 19,20-dihydroxy-15,16-epoxy-8(17),13(16),14-ent-labdatriene, 15,16-epoxy-12-oxo-8(17),13(16),14-ent-labdatrien-19,20-olide, were isolated, together with the known potamogetonin, from the aquatic plant Potamogeton natans. Their structures were determined on the basis of their chemical and spectral data. The compounds showed in vitro phytotoxicity against Raphidocelis subcapitata, a microalga used in aquatic tests. (C) 2001 Elsevier Science Ltd. All rights reserved.