5-乙基十一烷-6-酮 | 89355-13-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 5-乙基十一烷-6-酮
• 英文名称: 3-ethylundecan-6-one
• 英文别名: 5-ethylundecan-6-one
• CAS: 89355-13-5
• 化学式: C₁₃H₂₆O
• 分子量: 198.349
• InChiKey: KALOYZXPKPLLLM-UHFFFAOYSA-N

物化性质

• 沸点：
  252.5±8.0 °C(Predicted)
• 密度：
  0.824±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  14
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二正戊基酮 、 碘乙烷 在 lithium hexamethyldisilazane 作用下， 以 四氢呋喃 为溶剂， 反应 2.5h， 以42%的产率得到5-乙基十一烷-6-酮
  参考文献：
  名称：

  Ethyl-Branched Aldehydes, Ketones, and Diketones from Caimans (Caiman and Paleosuchus; Crocodylia, Reptilia)

  摘要：

  Secretions from the paracloacal glands of alligators (Alligator spp.) and caimans (Caiman spp., Melanosuchus niger, and Paleosuchus spp.) were examined by GC-MS. The secretions of the common caiman (C. crocodilus), the broadsnouted caiman (C. latirostris), the yacare caiman (C. yacare), the dwarf caiman (P. palpebrosus), and the smooth-fronted caiman (P. trigonatus) yielded a new family of 43 aliphatic carbonyl compounds that includes aldehydes, ketones, and beta-diketones with an ethyl branch adjacent to the carbonyl group. The identification of these glandular components and the syntheses and stereochemical investigations of selected compounds are described.

  DOI：

  10.1021/np0600797

文献信息

• IMIDAZOTHIAZOLE DERIVATIVES
  申请人：Daiichi Sankyo Company, Limited

  公开号：EP2103619A1

  公开（公告）日：2009-09-23

  There is provided a novel compound that inhibits interaction between murine double minute 2 (Mdm2) protein and p53 protein and exhibits anti-tumor activity. The present invention provides an imidazothiazole derivative represented by the following formula (1) having various substituents that inhibits interaction between Mdm2 protein and p53 protein and exhibits anti-tumor activity: wherein R1, R2, R3, R4, and R5 in the formula (1) each has the same meaning as defined in the specification.

  本发明提供了一种新型化合物，它能抑制小鼠双分 2（Mdm2）蛋白和 p53 蛋白之间的相互作用，并具有抗肿瘤活性。本发明提供了一种由下式（1）代表的咪唑噻唑衍生物，该衍生物具有各种取代基，可抑制 Mdm2 蛋白和 p53 蛋白之间的相互作用，并具有抗肿瘤活性： 其中，式（1）中的 R1、R2、R3、R4 和 R5 各具有与说明书中定义的相同含义。
• METHODS TO PRODUCE FUELS
  申请人：The Regents of the University of California

  公开号：EP2989073A2

  公开（公告）日：2016-03-02
• METHOD TO CONVERT FERMENTATION MIXTURE INTO FUELS
  申请人：Toste F. Dean

  公开号：US20140137465A1

  公开（公告）日：2014-05-22

  The present disclosure provides methods to produce ketones suitable for use as fuels and lubricants by catalytic conversion of an acetone-butanol-ethanol (ABE) fermentation product mixture that can be derived from biomass.
• US9790444B2
  申请人：——

  公开号：US9790444B2

  公开（公告）日：2017-10-17
• US9856427B2
  申请人：——

  公开号：US9856427B2

  公开（公告）日：2018-01-02