(4E)-2-hydroxy-4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-en-3-one | 62346-21-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (4E)-2-hydroxy-4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-en-3-one
• CAS: 62346-21-8
• 化学式: C₁₅H₂₂O₂
• 分子量: 234.33
• InChiKey: AXGJIHAKGFPXOX-JXMROGBWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] NEW TOPICAL USE OF ZERUMBONE<br/>[FR] NOUVELLE UTILISATION TOPIQUE DU ZÉRUMBONE
  申请人：SEDERMA SA

  公开号：WO2013105047A2

  公开（公告）日：2013-07-18

  The subject matter of the invention is the topical use of zerumbone preferably extracted from Zingiber zerumbet (L.) Smith for the treatment of the deficiencies of the capillary network of the skin, resulting in feelings of heaviness and tingling in the lower limbs. It also helps to treat micro-subcutaneous oedemas, including bags and/or dark circles under the eyes.
• [EN] NEW USE OF ZERUMBONE AND COMPOSITIONS COMPRISING ZERUMBONE<br/>[FR] NOUVELLE UTILISATION DU ZÉRUMBONE, ET COMPOSITIONS COMPRENANT LE ZÉRUMBONE
  申请人：SEDERMA SA

  公开号：WO2013105048A2

  公开（公告）日：2013-07-18

  According to the invention, zerumbone is used for a slimming topical treatment. Zerumbone is preferably extracted from Zingiber zerumbet (L.) Smith.In addition according to the invention zerumbone can be combined with an agent that mimics the beneficial effects of caloric restriction via a hormetic response, preferably a Globularia cordifolia extract,and/or a lipolytic additional active agent, preferably from the methylxanthine family, including caffeine, theophylline, theobromine or aminophylline.