(2E)-2-[(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylidene]-N-methoxy-N-methylhexanamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (2E)-2-[(4,5-dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)methylidene]-N-methoxy-N-methylhexanamide
• 化学式: C₁₈H₂₅NO₆
• 分子量: 351.4
• InChiKey: FVXPNMFNXSFKIW-ZRDIBKRKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  82.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Compounds, compositions and methods for treating oxidative DNA damage disorders
  申请人：Indiana University Research and Technology Corporation

  公开号：US11160770B2

  公开（公告）日：2021-11-02

  Compounds, compositions, and formulations, and accompanying methods useful for treating disorders arising from oxidative DNA damage, including oxidative DNA damage resulting from ionizing radiation or other therapy are described herein.

  本文描述了用于治疗氧化 DNA 损伤引起的疾病（包括电离辐射或其他疗法导致的氧化 DNA 损伤）的化合物、组合物和制剂，以及相应的方法。
• COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OXIDATIVE DNA DAMAGE DISORDERS
  申请人：Kelley Mark R.

  公开号：US20140128398A1

  公开（公告）日：2014-05-08

  Compounds, compositions, and formulations, and accompanying methods useful for treating disorders arising from oxidative DNA damage, including oxidative DNA damage resulting from ionizing radiation or other therapy are described herein.
• Compounds, Compositions and Methods for Treating Oxidative DNA Damage Disorders
  申请人：Indiana University and Research Technology Corporation

  公开号：US20160166521A1

  公开（公告）日：2016-06-16

  Compounds, compositions, and formulations, and accompanying methods useful for treating disorders arising from oxidative damage, including oxidative DNA damage resulting from ionizing radiation or other therapy are described.