N-[4-hydroxy-3-(4-octylphenyl)butyl]acetamide

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: N-[4-hydroxy-3-(4-octylphenyl)butyl]acetamide
• 化学式: C₂₀H₃₃NO₂
• 分子量: 319.5
• InChiKey: MWZLPJKTDVDGRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  23
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] FINGOLIMOD CONTAINING STABLE COMPOSITION<br/>[FR] COMPOSITION STABLE CONTENANT DU FINGOLIMOD
  申请人：SUN PHARMACEUTICAL IND LTD

  公开号：WO2014111955A1

  公开（公告）日：2014-07-24

  The present invention relates to a pharmaceutical composition comprising fingolimod and a weak acid cation exchange resin in the form of an ion-exchange complex and pharmaceutically acceptable excipients.
• [EN] PHARMACEUTICAL COMPOSITIONS OF FINGOLIMOD<br/>[FR] COMPOSITIONS PHARMACEUTIQUES DE FINGOLIMOD
  申请人：AIZANT DRUG RES PVT LTD

  公开号：WO2016042493A1

  公开（公告）日：2016-03-24

  The present invention relates to a pharmaceutical composition comprising fingolimod, a pharmaceutically acceptable salt thereof or a phosphate derivative, having less than about 0.5% concentration (w/w) of Impurity I after six months stability study at 40°C and 75% RH.