1-[(4-methylphenyl)methyl]-1H-indene;1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1-[(4-methylphenyl)methyl]-1H-indene;1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
• 化学式: C27H32O
• 分子量: 372.5
• InChiKey: RBCRUEREQWLGLN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.75
• 重原子数：
  28
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Ginger extract for the protection of stem cells
  申请人：Symrise AG

  公开号：EP2772245A1

  公开（公告）日：2014-09-03

  Summary Suggested is a ginger extract, comprising (a) 25 to 30 % b.w. [6]-gingerol (b) 5 to 10 % b.w. [8]-gingerol (c) 5 to 10 % b.w. [10]-gingerol (d) 1.5 to 4 % b.w. [6]-shogaol (e) 0.3 to 1.3 % b.w. [8]-shogaol; (f) 0.03 to 1 % b.w. [10]-shogaol; (g) 0.01 to 1 % b.w. zingerone, on condition that the amount of gingerols sums up to 35 to 50 % b.w. and the amount of shogaols sums up to 1.5 to 6 % b.w.

  内容摘要 建议一种生姜提取物，包括 (a) 25%至 30%（重量百分比）[6]-姜酚 (b) 5%至 10%（重量百分比）[8]-姜酚 (c) 5%至 10%重量百分比的[10]-姜酚 (d) 1.5 至 4 %（重量百分比）[6]-肖戈醇 (e) 0.3 至 1.3 % b.w. [8]-肖戈醇； (f) 0.03 至 1 %（重量百分比）[10]-肖高醇； (g) 0.01 至 1 %（重量百分比）的姜辣素，条件是姜辣素的含量达到 35 至 50 %（重量百分比），肖酚的含量达到 1.5 至 6 %（重量百分比）。
• COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES
  申请人：Symrise AG

  公开号：EP3108941A1

  公开（公告）日：2016-12-28

  Suggested are compositions comprising or consisting of specific polyalkylene glycol derivative as pharmaceutical actives for preventing, treating and/or curing itchy conditions of human skin and scalp, and/or providing a PAR-2 antagonistic effect to human skin and scalp.

  建议使用由特定聚亚烷基二醇衍生物组成的组合物作为药物活性成分，用于预防、治疗和/或治愈人体皮肤和头皮瘙痒症，和/或为人体皮肤和头皮提供 PAR-2 拮抗作用。
• Urea derivatives for the protection of stem cells
  申请人：Symrise AG

  公开号：EP2862852B1

  公开（公告）日：2018-07-04
• REDUCTION OF STINGING SENSATION ON SKIN
  申请人：Symrise AG

  公开号：EP3373895B1

  公开（公告）日：2020-08-19
• ANTIMICROBIAL ACTIVITY OF FATTY ACID ESTERS AND COMBINATIONS THEREOF
  申请人：SYMRISE AG

  公开号：US20220117867A1

  公开（公告）日：2022-04-21

  The present invention primarily relates to the use of a fatty acid ester, or a mixture comprising, or consisting of, two or more fatty acid esters, in a cosmetic product for inhibiting growth of microorganisms on a mammal's skin or mucosa, and/or preserving the cosmetic product against microbial growth, wherein the fatty acid ester, or at least one of the two or more fatty acid esters in the mixture, is selected from the group consisting of 3-hydroxypropyl caprylate, 3-hydroxypropyl undecylenate and glyceryl monoundecylenate.