2-(chloromethyl)-5-[(4-chlorophenyl)methyl]-2-methyl-1-(1H-1,2,4-triazol-5-ylmethyl)cyclopentan-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(chloromethyl)-5-[(4-chlorophenyl)methyl]-2-methyl-1-(1H-1,2,4-triazol-5-ylmethyl)cyclopentan-1-ol
• 化学式: C₁₇H₂₁Cl₂N₃O
• 分子量: 354.3
• InChiKey: MFJZTYPHBREACY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  23
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  61.8
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• METHOD FOR MANUFACTURING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE AND METHOD FOR MANUFACTURING AZOLE DERIVATIVE
  申请人：Kureha Corporation

  公开号：US20140336389A1

  公开（公告）日：2014-11-13

  In order to manufacture a higher yield of a 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative, the present invention is a method for manufacturing a compound represented by General Formula (I) which includes a step for reducing a compound represented by General Formula (II) using a hydride-type reducing agent in an aprotic solvent having an amide bond.

  为了生产更高产量的4-苄基-1-甲基-6-氧代双环[3,2,0]庚烷衍生物，本发明提供了一种制造通式（I）所代表化合物的方法，其中包括使用无水溶剂中的酰胺键的氢化还原剂还原通式（II）所代表的化合物的步骤。
• METHOD FOR PRODUCING 4-BENZYL-1-METHYL-6-OXABICYCLO[3,2,0]HEPTANE DERIVATIVE AND METHOD FOR PRODUCING AZOLE DERIVATIVE
  申请人：Kureha Corporation

  公开号：EP2778164A1

  公开（公告）日：2014-09-17

  In order to manufacture a higher yield of a 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative, the present invention is a method for manufacturing a compound represented by General Formula (I) which includes a step for reducing a compound represented by General Formula (II) using a hydride-type reducing agent in an aprotic solvent having an amide bond.

  为了制造收率更高的 4-苄基-1-甲基-6-氧杂双环[3,2,0]庚烷衍生物，本发明是一种制造通式（I）所代表化合物的方法，该方法包括在具有酰胺键的烷基溶剂中使用氢化物型还原剂还原通式（II）所代表化合物的步骤。
• US9051298B2
  申请人：——

  公开号：US9051298B2

  公开（公告）日：2015-06-09