12-Deoxyphorbol-13-(2-methylbutyrate) | 28152-97-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 12-Deoxyphorbol-13-(2-methylbutyrate)
• 英文别名: [(1R,2S,6R,10S,11R,13S,15R)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-methylbutanoate
• CAS: 28152-97-8
• 化学式: C₂₅H₃₆O₆
• 分子量: 432.5
• InChiKey: UTWPUNYNNNYPEZ-ABNKIXKLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  31
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  104
• 氢给体数：
  3
• 氢受体数：
  6

文献信息

• COMPOSITIONS AND METHODS OF USE OF PHORBOL ESTERS IN THE TREATMENT OF NEOPLASMS
  申请人：Biosuccess Biotech Co. Ltd.

  公开号：US20210000780A1

  公开（公告）日：2021-01-07

  Methods and compositions containing a phorbol ester or a derivative of a phorbol ester are provided for the treatment of chronic and acute conditions. Such conditions may be caused by disease, be symptoms, treatments, or sequelae of disease. The phorbol esters described are particularly useful in the treatment of neoplastic diseases and/or managing the side effects of chemotherapeutic and radiotherapeutic treatments of neoplastic diseases.