5-苯基-2-(2-苯基喹啉-4-基)-1,3-恶唑 | 102542-89-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 中文名称: 5-苯基-2-(2-苯基喹啉-4-基)-1,3-恶唑
• 中文别名: 喹啉,2-苯基-4-(5-苯基-2-[口噁]唑基)-
• 英文名称: 5-phenyl-2-(2-phenyl-4-quinolyl)oxazole
• 英文别名: 2-phenyl-4-(5-phenyl-oxazol-2-yl)-quinoline；2-Phenyl-4-(5-phenyl-oxazol-2-yl)-chinolin；Quinoline, 2-phenyl-4-(5-phenyl-2-oxazolyl)-；5-phenyl-2-(2-phenylquinolin-4-yl)-1,3-oxazole
• CAS: 102542-89-2
• 化学式: C₂₄H₁₆N₂O
• 分子量: 348.404
• InChiKey: LOFMBQYJKQXLHE-UHFFFAOYSA-N

物化性质

• 熔点：
  157-158 °C
• 沸点：
  591.6±60.0 °C(Predicted)
• 密度：
  1?+-.0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  38.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-苯基-4-喹啉羧酸 在 硫酸 、 N,N'-二异丙基碳二亚胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 5-苯基-2-(2-苯基喹啉-4-基)-1,3-恶唑
  参考文献：
  名称：

  Combinatorial discovery of novel fluorescent dyes based on Dapoxyl™

  摘要：

  We have developed a combinatorial method for the fast and effective synthesis of a library based on a known fluorescent dye, Dapoxyl(TM) using parallel solution-phase chemistry. By screening the 140 new compounds using fluorescence-based assays, we identified three new fluorescent dyes with novel properties. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)00999-1

文献信息

• Liquid Scintillators. V. Absorption and Fluorescence Spectra of 2,5-Diaryloxazoles and Related Compounds¹
  作者：Donald G. Ott、F. Newton Hayes、Elizabeth Hansbury、Vernon N. Kerr

  DOI：10.1021/ja01577a032

  日期：1957.10

  Ultraviolet absorption data and wave lengths of maximum emission and mean wave lengths of fluorescence are presented. The synthesis and evaluation as scintillator solutes of previously unreported compounds are given.

  提供了紫外吸收数据和最大发射波长和荧光平均波长。给出了以前未报道的化合物作为闪烁体溶质的合成和评价。
• Synthesis of N-heterocyclic analogues of 2,5-diaryloxazoles
  作者：B. M. Krasovitskii、K. M. Dyumaev、L. Sh. Afanasiadi、I. N. Tur、A. A. Verezubova、L. M. Ptyagina

  DOI：10.1007/bf00519954

  日期：1986.2
• KRASOVITSKIJ, B. M.;DYUMAEV, K. M.;AFANASIADI, L. SH.;TUR, I. N.;VEREZUBO+, XIMIYA GETEROTSIKL. SOEDIN., 1986, N 2, 279-280
  作者：KRASOVITSKIJ, B. M.、DYUMAEV, K. M.、AFANASIADI, L. SH.、TUR, I. N.、VEREZUBO+

  DOI：——

  日期：——
• Combinatorial discovery of novel fluorescent dyes based on Dapoxyl™
  作者：Qing Zhu、Hai-Shin Yoon、Puja B. Parikh、Young-Tae Chang、Shao Q. Yao

  DOI：10.1016/s0040-4039(02)00999-1

  日期：2002.7

  We have developed a combinatorial method for the fast and effective synthesis of a library based on a known fluorescent dye, Dapoxyl(TM) using parallel solution-phase chemistry. By screening the 140 new compounds using fluorescence-based assays, we identified three new fluorescent dyes with novel properties. (C) 2002 Elsevier Science Ltd. All rights reserved.