(E)-4-(3,4-dimethylphenyl)-2-methylbut-3-en-2-ol | 96307-79-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂醇
• 英文名称: (E)-4-(3,4-dimethylphenyl)-2-methylbut-3-en-2-ol
• CAS: 96307-79-8
• 化学式: C₁₃H₁₈O
• 分子量: 190.285
• InChiKey: URGBAVYTLBDDQW-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-4-(3,4-dimethylphenyl)-2-methylbut-3-en-2-ol 在 五氟化锑 、 氟磺酸 作用下， 以 various solvent(s) 为溶剂， 生成 1,2-dimethyl-4-(3-methylbut-1-enyl)benzene
  参考文献：
  名称：

  Considered stable cations. 259. Application of the Gassman-Fentiman tool of increasing electron demand to the carbon-13 NMR spectroscopic study of 1-aryl-3-methylbut-2-enyl (allylic) and 2-arylpent-3-yn-2-yl (propargylic) cations

  摘要：

  DOI：

  10.1021/ja00299a030
• 作为产物：
  描述：

  (E)-1,2-dimethyl-4-(2-nitrovinyl)benzene 、 异丙醇 在 二叔丁基过氧化物 、 copper diacetate 作用下， 以61%的产率得到(E)-4-(3,4-dimethylphenyl)-2-methylbut-3-en-2-ol
  参考文献：
  名称：

  Copper-Catalyzed Alkenylation of Alcohols with β-Nitrostyrenes via a Radical Addition–Elimination Process

  摘要：

  A new method for the preparation of allylic alcohol derivatives has been developed via a radical mechanism using DTBP as the radical initiator promoted by copper salt. The C(sp(3))-H bond in various alcohols, toluene derivatives, and alkanes were successfully converted into C-C bonds to yield the desired products in moderate to good yields.

  DOI：

  10.1055/s-0034-1380445

文献信息

• Copper-Catalyzed Alkenylation of Alcohols with β-Nitrostyrenes via a Radical Addition–Elimination Process
  作者：Yan-qin Yuan、Sheng-rong Guo

  DOI：10.1055/s-0034-1380445

  日期：——

  A new method for the preparation of allylic alcohol derivatives has been developed via a radical mechanism using DTBP as the radical initiator promoted by copper salt. The C(sp(3))-H bond in various alcohols, toluene derivatives, and alkanes were successfully converted into C-C bonds to yield the desired products in moderate to good yields.
• Considered stable cations. 259. Application of the Gassman-Fentiman tool of increasing electron demand to the carbon-13 NMR spectroscopic study of 1-aryl-3-methylbut-2-enyl (allylic) and 2-arylpent-3-yn-2-yl (propargylic) cations
  作者：G. K. Surya Prakash、V. V. Krishnamurthy、George A. Olah、D. G. Farnum

  DOI：10.1021/ja00299a030

  日期：1985.6