2β,9α-dihydroxyclovane

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2β,9α-dihydroxyclovane
• 英文别名: clovane-2α,9β-diol；clovane-2β,9α-diol；(1S,2S,8R,9R)-4,4,8-trimethyltricyclo[6.3.1.01,5]dodecane-2,9-diol
• 化学式: C₁₅H₂₆O₂
• 分子量: 238.37
• InChiKey: BWXJQHJHGMZLBT-SLPXSTGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  石竹素 、 丙烯醛 在 clay 作用下， 以 二氯甲烷 为溶剂， 反应 2.5h， 以13%的产率得到13β-vinyl-1,5,5-trimethyl-8-methylene-4β,7α-2,14-dioxatricyclo[9.3.0.0^4,7]tetradecane
  参考文献：
  名称：

  摘要：

  Products of reaction between caryophyllene 4beta,5alpha-epoxide and carbonyl compounds (acrolein, crotonaldehyde, alpha-methacrolein, and acetone) were synthesized on clay. Two diastereomers in reaction with each aldehyde and a single isomer with acetone were obtained. In reaction of the epoxide with acetone an isomerization product was isolated, 4,4,9-trimethyltricyclo[6.2.2.0(1.5)]dodec-9-en-2beta-ol that was unknown before.

  DOI：

  10.1023/a:1016595005735

文献信息

• ——
  作者：L. E. Tatarova、D. V. Korchagina、V. A. Barkhash

  DOI：10.1023/a:1016595005735

  日期：——

  Products of reaction between caryophyllene 4beta,5alpha-epoxide and carbonyl compounds (acrolein, crotonaldehyde, alpha-methacrolein, and acetone) were synthesized on clay. Two diastereomers in reaction with each aldehyde and a single isomer with acetone were obtained. In reaction of the epoxide with acetone an isomerization product was isolated, 4,4,9-trimethyltricyclo[6.2.2.0(1.5)]dodec-9-en-2beta-ol that was unknown before.