6-nonen-2-one | 82873-10-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 6-nonen-2-one
• 英文别名: non-6-en-2-one
• CAS: 82873-10-7
• 化学式: C₉H₁₆O
• 分子量: 140.225
• InChiKey: TVHAWOPAFXXIQM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  6-nonen-2-one 在 bis(acetylacetonato)dioxidomolybdenum(VI) 作用下， 以 苯 为溶剂， 反应 3.0h， 生成 (1R,5S,7R)-7-乙基-5-甲基-6,8-二氧杂双环[3.2.1]辛烷 、 endo-brevicomin
  参考文献：
  名称：

  Attractant pheromones of coleoptera. Communication 1. Simple synthesis of exo- and endo-brevicomins using the oxy-cope rearrangement

  摘要：

  DOI：

  10.1007/bf00948528
• 作为产物：
  描述：

  4-ethyl-3-methyl-1,5-hexadien-3-ol 以 various solvent(s) 为溶剂， 以69%的产率得到6-nonen-2-one
  参考文献：
  名称：

  Effect of alkyl substituents in 1,5-dien-3-ols on low-temperature sigmatropic [3,3] rearrangement catalyzed by palladium(II) complexes

  摘要：

  DOI：

  10.1007/bf00953859

文献信息

• Method for Producing Aldehyde and Ketone
  申请人：Yamashita Miyoshi

  公开号：US20110282102A1

  公开（公告）日：2011-11-17

  Provided is a highly efficient method for the production of aldehydes and ketones, which is inexpensive, exhibits high reactivity, and is capable of easy separation of byproduct after the reaction. More particularly, there is provided a method for producing an aldehyde or a ketone, comprising at least an oxidation step of oxidizing a primary alcohol or a secondary alcohol in the presence of a polymeric carbodiimide represented by the following formula (1) and having a weight-average molecular weight of 300 to 5000, and a sulfoxide compound, together with an acid and a base, or together with a salt of the acid and the base.

  提供了一种高效的生产醛和酮的方法，该方法廉价、具有高反应性，并能够在反应后轻松分离副产物。更具体地，提供了一种生产醛或酮的方法，包括至少一个氧化步骤，即在聚合物碳二亚胺（表示为以下式（1）且具有分子量为300至5000的重均分子量）和亚砜化合物的存在下氧化一级醇或二级醇，以及酸和碱，或者酸和碱的盐。
• A novel bicyclic ketal fragmentation reaction
  作者：Michael Bjorklund、Jong Gab Jun、Bradford P. Mundy

  DOI：10.1016/s0040-4039(00)98681-7

  日期：1985.1

  Bicyclic ketals of the 6,8-dioxabicyclo[3.2.1]octane series are specifically cleaved to give δ, ε-unsaturated ketones by treatment of the ketal with acetyl iodide.

  通过用乙酰碘化物处理缩酮，将6,8-二氧杂双环[3.2.1]辛烷系列的双环缩酮具体裂解，得到δ，ε-不饱和酮。
• Substituted quinolin-4-ylamine analogues
  申请人：Bakthavatchalam Rajagopal

  公开号：US20050070547A1

  公开（公告）日：2005-03-31

  Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders-are provided, as are methods for using such ligands for receptor localization studies.

  本发明提供了替代喹啉-4-胺类似物。这些化合物是配体，可用于调节体内或体外特定受体的活性，并且在治疗与人类、家畜伴侣动物和牲畜动物的病理性受体激活相关的疾病方面特别有用。还提供了制备这些药物组合物和使用它们治疗此类疾病的方法，以及使用这些配体进行受体定位研究的方法。
• SUBSTITUTED QUINOLIN-4-YLAMINE ANALOGUES
  申请人：Bakthavatchalam Rajagopal

  公开号：US20090286767A1

  公开（公告）日：2009-11-19

  Substituted quinolin-4-ylamine analogues are provided. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using them to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.

  提供了替代的喹啉-4-胺类似物。这些化合物是配体，可以用于体内或体外调节特定受体的活性，并且在治疗与人类、家养伴侣动物和家畜动物的病理性受体激活相关的情况方面特别有用。提供了制药组合物和使用它们治疗这些疾病的方法，以及使用这样的配体进行受体定位研究的方法。
• Prostaglandin analogue triazole derivatives, processes for their preparation and a pharmaceutical composition containing them
  申请人：BEECHAM GROUP PLC

  公开号：EP0007180A1

  公开（公告）日：1980-01-23

  Compounds of the formula (I): wherein n is 3 to 5; Y is -CH2-CH2, -CH =CH- or C≡C; L is O or S; R, is C1-4 alkyl; R: is hydrogen, C1-4alkyl or phenyl; R3 is hydroxy or protected hydroxy; R, is hydrogen, C1-9alkyl, C3-8cycloalkyl, phenyl, naphthyl, any of which phenyl moieties or naphthyl moieties may be substituted by one or more halogen, trifluoromethyl, C1-6alkyl, nyd- roxy, C1-6alkoxy, phenyl C1-6alkoxy or nitro groups; or R2 and R4 taken with the carbon atom to which they are joined represent a C5-ecycloalkyl group; and R. is C1-6alkyl, having similar activity to natural prostaglandins, two processes for their preparation, intermediates useful in said processes and pharmaceutical compositions containing the novel compounds of the formula (I) are disclosed.

  式 (I) 的化合物： 其中 n 为 3 至 5； Y 是-CH2-CH2、-CH =CH- 或 C≡C L 是 O 或 S R是C1-4烷基； R：是氢、C1-4 烷基或苯基； R3 是羟基或受保护的羟基； R：是氢、C1-9烷基、C3-8环烷基、苯基、萘基，其中任何苯基或萘基可被一个或多个卤素、三氟甲基、C1-6烷基、硝基、C1-6烷氧基、苯基 C1-6烷氧基或硝基取代；或 R2 和 R4 与它们连接的碳原子一起代表一个 C5-ecycloalkyl 基团；并且 R. 是 C1-6烷基，具有与天然前列腺素相似的活性，公开了制备它们的两种工艺、在所述工艺中有用的中间体以及含有式 (I) 新型化合物的药物组合物。