3-(Dicyclopropylmethylidene)-4-[1-(2,5-dimethylfuran-3-yl)ethylidene]oxolane-2,5-dione | 176043-68-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3-(Dicyclopropylmethylidene)-4-[1-(2,5-dimethylfuran-3-yl)ethylidene]oxolane-2,5-dione
• 英文别名: 3-(dicyclopropylmethylidene)-4-[1-(2,5-dimethylfuran-3-yl)ethylidene]oxolane-2,5-dione
• CAS: 176043-68-8
• 化学式: C₁₉H₂₀O₄
• 分子量: 312.365
• InChiKey: FZKPXLWLLPOXPG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  56.5
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3-(Dicyclopropylmethylidene)-4-[1-(2,5-dimethylfuran-3-yl)ethylidene]oxolane-2,5-dione 以 吡啶 为溶剂， 反应 4.0h， 以0.95 g的产率得到(E)-dicyclopropylidene(2,5-dimethyl-3-furyl)ethylidenesuccinic anhydride
  参考文献：
  名称：

  A convenient method for conversion of the Z-isomer to the E-isomer from a mixture containing both isomers of fulgides

  摘要：

  A new method for the conversion of the Z-isomer of unsymmetrical substituted bis-methylenesuccinic anhydrides, 'fulgides', to their geometrical E-isomers was achieved by heating the Z-isomer under reflux or a mixture of both isomers in pyridine to give the E-isomer in near quantitative yield. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)01514-9
• 作为产物：
  描述：

  2-Dicyclopropylmethylene-3-[1-(2,5-dimethyl-furan-3-yl)-eth-(E)-ylidene]-succinic acid 在 乙酰氯 作用下， 以59.5%的产率得到3-(Dicyclopropylmethylidene)-4-[1-(2,5-dimethylfuran-3-yl)ethylidene]oxolane-2,5-dione
  参考文献：
  名称：

  Fulgides和光致变色。（E）-和（Z）-5-二氰基亚甲基-4-二环丙基亚甲基-3- [1-（2,5-二甲基-3-呋喃基）亚乙基]四氢呋喃-2-酮的合成

  摘要：

  报道了（E + Z）-5-二氰基亚甲基-4-二环丙基亚甲基-3- [1-（2，5-二甲基-3-呋喃基）亚乙基]四氢呋喃-2-酮（3）的合成和光化学性质。

  DOI：

  10.1016/0040-4039(95)00632-m

文献信息

• Fulgides and photochromism. Synthesis of (E)- and (Z)-5-dicyanomethylene-4-dicyclopropylmethylene-3-[1-(2,5-dimethyl-3-furyl)ethylidene]tetrahydrofuran-2-one
  作者：Zhiyuan Sun、Ramachandra S. Hosmane、Maher Tadros

  DOI：10.1016/0040-4039(95)00632-m

  日期：1995.5

  The synthesis and photochemical property of (E+Z)-5-dicyanomethylene-4-dicyclopropylmethylene-3-[1-(2,5-dimethyl-3-furyl)ethylidene]tetrahydrofuran-2-one (3) are reported.

  报道了（E + Z）-5-二氰基亚甲基-4-二环丙基亚甲基-3- [1-（2，5-二甲基-3-呋喃基）亚乙基]四氢呋喃-2-酮（3）的合成和光化学性质。
• A convenient method for conversion of the Z-isomer to the E-isomer from a mixture containing both isomers of fulgides
  作者：Abdullah Mohamed Asiri

  DOI：10.1016/s0040-4039(02)01514-9

  日期：2002.9

  A new method for the conversion of the Z-isomer of unsymmetrical substituted bis-methylenesuccinic anhydrides, 'fulgides', to their geometrical E-isomers was achieved by heating the Z-isomer under reflux or a mixture of both isomers in pyridine to give the E-isomer in near quantitative yield. (C) 2002 Elsevier Science Ltd. All rights reserved.