4-Acetyl-2-methyl-thiophenol | 17067-24-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 4-Acetyl-2-methyl-thiophenol
• 英文别名: 1-(3-Methyl-4-sulfanylphenyl)ethanone
• CAS: 17067-24-2
• 化学式: C₉H₁₀OS
• 分子量: 166.244
• InChiKey: JJWURSKHYARVBM-UHFFFAOYSA-N

物化性质

• 熔点：
  30-31 °C
• 沸点：
  146-147 °C(Press: 6 Torr)
• 密度：
  1.109±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  18.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-[(2-甲基苯基)硫代]-乙酸 在 三氯化铝 、 硫酸 、 双氧水 、 溶剂黄146 作用下， 以 二硫化碳 、 硝基苯 为溶剂， 生成 4-Acetyl-2-methyl-thiophenol
  参考文献：
  名称：

  Electrophilic Substitution of the Benzenethiols. II. Acylbenzene- and Acyltoluenethiols^1,2

  摘要：

  DOI：

  10.1021/jo01046a035

文献信息

• MALONAMIDE DERIVATIVES WITH ANTITHROMBOTIC ACTIVITY
  申请人：STEINHAGEN Henning

  公开号：US20100249101A1

  公开（公告）日：2010-09-30

  The present invention relates to compounds of formula I, The compounds of formula I are valuable pharmacologically active compounds. They exhibit a strong anti-thrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardio-vascular disorders like thromboembolic diseases or restenoses. They are inhibitors of the blood clotting enzymes, especially factor VIIa and can in general be applied in conditions in which an undesired activity of factor VIIa is present or for the cure or prevention of which an inhibition of factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.

  本发明涉及式I的化合物，式I的化合物是有价值的药理活性化合物。它们表现出强烈的抗血栓作用，适用于治疗和预防心血管疾病，如血栓栓塞性疾病或再狭窄。它们是血凝酶酶的抑制剂，特别是因子VIIa，通常可应用于因子VIIa不良活性存在的情况或治愈或预防需要抑制因子VIIa的情况。此外，本发明还涉及式I化合物的制备方法，它们的用途，特别是作为药物的活性成分，以及包含它们的制药制剂。
• Golf ball
  申请人：Dunlop Sports Co., Ltd.

  公开号：EP2668976A1

  公开（公告）日：2013-12-04

  A golf ball 2 includes a core 4, a mid layer 6, and a cover 10. The core 4 includes a center 16, a first envelope layer 18, and a second envelope layer 20. The first envelope layer 18 is formed by a first rubber composition being crosslinked. The second envelope layer 20 is formed by a second rubber composition being crosslinked. The first rubber composition and/or the second rubber composition include: a base rubber; a co-crosslinking agent; a crosslinking initiator; and an acid and/or a salt. The co-crosslinking agent is (1) an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms; and/or (2) a metal salt of an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms.

  高尔夫球 2 包括球芯 4、中层 6 和外层 10。球芯 4 包括中心 16、第一包胶层 18 和第二包胶层 20。第一包层 18 由交联的第一橡胶成分形成。第二包胶层 20 由交联的第二橡胶组合物形成。第一橡胶组合物和/或第二橡胶组合物包括：基础橡胶；共交联剂；交联引发剂；酸和/或盐。共交联剂是（1）具有 3 至 8 个碳原子的 α，β-不饱和羧酸；和/或（2）具有 3 至 8 个碳原子的 α，β-不饱和羧酸的金属盐。
• GOLF BALL
  申请人：Dunlop Sports Co., Ltd.

  公开号：EP3156441A1

  公开（公告）日：2017-04-19

  A golf ball 2 includes a core 4, a first mid layer 6, a second mid layer 8, and a cover 12. The core 4 includes a center 18 and an envelope layer 20. The center 18 is formed by crosslinking a first rubber composition, and the envelope layer 20 is formed by crosslinking a second rubber composition. The first rubber composition or the second rubber composition includes a base rubber, a co-crosslinking agent, a crosslinking initiator, and an acid and/or a salt. The co-crosslinking agent is: (1) an α, β-unsaturated carboxylic acid having 3 to 8 carbon atoms; and/or (2) a metal salt of an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms. A hardness Hm2 of the second mid layer 8 is greater than a hardness Hm1 of the first mid layer 6. The hardness Hm2 is greater than a hardness Hc of the cover 12.

  高尔夫球 2 包括球芯 4、第一中层 6、第二中层 8 和外层 12。球芯 4 包括中心 18 和包层 20。中心 18 由第一种橡胶组合物交联形成，包层 20 由第二种橡胶组合物交联形成。第一种橡胶组合物或第二种橡胶组合物包括基础橡胶、共交联剂、交联引发剂以及酸和/或盐。共交联剂为 (1) 具有 3 至 8 个碳原子的 α、β-不饱和羧酸；和/或 (2) 具有 3 至 8 个碳原子的 α、β-不饱和羧酸的金属盐。 第二中间层 8 的硬度 Hm2 大于第一中间层 6 的硬度 Hm1。硬度 Hm2 大于盖板 12 的硬度 Hc。
• Solid golf ball
  申请人：——

  公开号：US20030144425A1

  公开（公告）日：2003-07-31

  The present invention provides a solid golf ball having exceptional rebound characteristics and flight performance, as well as good shot feel. The present invention relates to a solid golf ball comprising at least one layer of a core, and at least one layer of a cover formed on the core, wherein at least one layer including the inmost layer of the core is formed by vulcanizing a rubber composition comprising a base rubber, a co-crosslinking agent, a vulcanization initiator and a filler, the core has a center hardness in JIS-C hardness of 40 to 60, a surface hardness in JIS-C hardness of 80 to 95 and a hardness difference (B−A) between a hardness in JIS-C hardness at a distance of 5 mm from the center point of the core (B) and the center hardness (A) of not less than 1 to less than 10.

  本发明提供了一种具有优异反弹特性和飞行性能以及良好击球手感的实心高尔夫球。本发明涉及一种实心高尔夫球，包括至少一层球芯和至少一层在球芯上形成的包胶，其中包括球芯最内层在内的至少一层包胶是通过硫化橡胶组合物形成的，该橡胶组合物包括基础橡胶、共交联剂、硫化引发剂和填料、夹芯的中心硬度（JIS-C 硬度）为 40 至 60，表面硬度（JIS-C 硬度）为 80 至 95，距夹芯中心点 5 毫米处的 JIS-C 硬度（B）与中心硬度（A）之间的硬度差（B-A）不小于 1 至小于 10。
• US5113019A
  申请人：——

  公开号：US5113019A

  公开（公告）日：1992-05-12