7-氯庚酸乙酯 | 26040-65-3

• 物质功能分类: 化学试剂 - 有机试剂 - 酯类
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 7-氯庚酸乙酯
• 英文名称: 7-Chlor-heptansaeureethylester
• 英文别名: Ethyl 7-chloroheptanoate
• CAS: 26040-65-3
• 化学式: C₉H₁₇ClO₂
• mdl: MFCD00038767
• 分子量: 192.686
• InChiKey: MTVFBQCYLUWYAS-UHFFFAOYSA-N

物化性质

• 沸点：
  122-123 °C(Press: 11 Torr)
• 密度：
  1.0110 g/cm3
• 保留指数：
  1339

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.888
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  7-氯庚酸乙酯 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成 N⁹-(ω-hydroxy-n-heptyl)adenine
  参考文献：
  名称：

  摘要：

  N-9-Polymethylene derivatives of adenine and hypoxanthine with various functional groups in the omega -position of the alkyl substituent were synthesized. Their physicochemical properties and effect on the HIV reverse transcriptase and DNA topoisomerase I were studied.

  DOI：

  10.1023/a:1011377103793
• 作为产物：
  描述：

  乙醇 、 7-氯庚酸 在 sodium chloride 作用下， 生成 7-氯庚酸乙酯
  参考文献：
  名称：

  Eryshev,B.Ya. et al., Journal of applied chemistry of the USSR, 1979, vol. 52, p. 589 - 591

  摘要：

  DOI：

文献信息

• N-Substituted .omega.-(2-oxo-4-imidazolin-1-yl) alcanoic acids and salts
  申请人：A. Nattermann & Cie GmbH

  公开号：US04349684A1

  公开（公告）日：1982-09-14

  The present invention refers to N-substituted .omega.-(2-oxo-4-imidazolin-1-yl) alcanoic acids as well as salts and esters thereof having the general formula I ##STR1## The compounds are useful, for example, as antiallergics, antiasthmatics, etc.

  本发明涉及N-取代的ω-(2-氧代-4-咪唑啉-1-基)脂肪酸及其盐和酯，其具有一般式I。这些化合物可用作抗过敏剂、抗哮喘剂等。
• Triphenylimidazolyloxyalkanoic acids and their derivatives and a process
  申请人：A. Nattermann & Cie GMBH

  公开号：US04460598A1

  公开（公告）日：1984-07-17

  The invention relates to new triphenylimidazolyloxyalkanoic acids of the general formula I ##STR1## and a process for the treatment of thromboembolic, inflammatory and/or atherosclerotic diseases in humans by using the same.

  这项发明涉及一种新的三苯基咪唑氧烷酸，其通式为I，并提供了一种治疗人类血栓栓塞、炎症和/或动脉粥样硬化疾病的方法。
• .omega.-(2-Oxo-benzazolinyl)-alkanoic acid derivatives
  申请人：A. Nattermann & Cie GmbH

  公开号：US04377695A1

  公开（公告）日：1983-03-22

  The present invention refers to new .omega.-(2-oxo-benzazolinyl)-alkanoic acids as well as salts and esters thereof having the general formula I ##STR1## and having antiinflammatory, analgesic and antithrombotic activity.

  本发明涉及具有通式I的新的.omega.-(2-氧代苯并咪唑基)-烷酸，以及具有抗炎、镇痛和抗血栓活性的盐和酯。
• Photoredox/Nickel Dual Catalysis for the C(sp³ )-C(sp³ ) Cross-Coupling of Alkylsilicates with Alkyl Halides
  作者：Christophe Lévêque、Vincent Corcé、Ludwig Chenneberg、Cyril Ollivier、Louis Fensterbank

  DOI：10.1002/ejoc.201601571

  日期：2017.4.18

  Alkylsilicates were engaged under photoredox/nickel dual catalysis conditions with alkyl halides for the first time. The C(sp3)–C(sp3) cross-coupling products were obtained in moderate yields and were accompanied by the homocoupling products of the alkyl halide derivatives. These promising findings are strongly suggestive of the high synthetic potential of the dual catalytic approach for the forging of

  烷基硅酸盐首次在光氧化还原/镍双催化条件下与烷基卤化物结合。C(sp3)–C(sp3) 交叉偶联产物以中等产率获得，并伴随着烷基卤衍生物的均偶联产物。这些有希望的发现强烈暗示了双催化方法在锻造烷基碳-碳键方面的高合成潜力。
• Copper-Catalyzed B(dan)-Installing Carboboration of Alkenes
  作者：Ikuo Kageyuki、Itaru Osaka、Ken Takaki、Hiroto Yoshida

  DOI：10.1021/acs.orglett.6b03820

  日期：2017.2.17

  Carboboration of alkenes was found to occur readily with an unsymmetrical diboron [(pin)B–B(dan)] and alkyl halides under copper catalysis, leading to the direct formation of protected alkylboron compounds via synchronous C–C and C–B bond-forming processes. The B(dan) moiety was solely installed into the organic frameworks with the regioselective attachment to a terminal carbon of alkenes employed

  发现不对称的二硼[[pin] B-B（dan）]和烷基卤在铜催化下很容易发生烯烃的碳硼化，从而通过同步的CC和C-B键直接形成受保护的烷基硼化合物。成型过程。仅将B（dan）部分安装到有机骨架中，并在所用烯烃的末端碳上进行区域选择性连接。