actinostemmoside C | 108906-62-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: actinostemmoside C
• 英文别名: (2S,3R,4S,5S,6R)-2-[(Z,2S)-2-[(3S,5S,7S,8R,9R,10S,13R,14R,17S)-3,7-dihydroxy-8-(hydroxymethyl)-4,4,10,14-tetramethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-7-hydroxy-6-methylhept-5-en-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
• CAS: 108906-62-3
• 化学式: C₃₆H₆₂O₁₀
• 分子量: 654.882
• InChiKey: HGYRBMZHJGVFPT-OGYWNDFZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  46
• 可旋转键数：
  9
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  180
• 氢给体数：
  8
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  actinostemmoside C 在 copper(II) sulfate 作用下， 以 甲醇 、 水 为溶剂， 反应 144.0h， 生成 (S,Z)-6-((1S,3aR,3bR,7aS,8aS,10S,12aS,12bR,14aR)-10-hydroxy-3a,6,6,9,9,12a-hexamethylhexadecahydro-4H-cyclopenta[7,8]phenanthro[9,8a-d][1,3]dioxin-1-yl)-2-methylhept-2-ene-1,6-diol
  参考文献：
  名称：

  Studies on the constituents of Actinostemma lobatum Maxim. I Structures of actinostemmosides A, B, C and D, dammarane triterpene glycosides isolated from the herb.

  摘要：

  为Actinostemma lobatum MAXIM 的干燥草本。 （葫芦科）分离了四种达玛烷型三萜糖苷，分别命名为放线菊苷 A、B、C 和 D，并根据化学和光谱证据阐明了它们的结构。 Actinostemmosides A、B 和 C 被鉴定为 3β, 6α, 20, 27-四羟基- (20S) -dammar-24-ene, 3β, 7β, 20, 27-四羟基- ( 20S) -dammar-24-ene 和 3β, 7β, 18, 20, 27-五羟基- (20S) -dammar-24-ene 分别，以及放线菌苷 D，作为 α-L-吡喃鼠李糖基- (1→2) 3β,6α,20,27-四羟基-(20R)-dammar-24-ene的-β-D-吡喃葡萄糖苷。

  DOI：

  10.1248/cpb.35.553

文献信息

• Studies on the constituents of Actinostemma lobatum Maxim. I Structures of actinostemmosides A, B, C and D, dammarane triterpene glycosides isolated from the herb.
  作者：MASAYO IWAMOTO、TOSHIHIRO FUJIOKA、HIKARU OKABE、KUNIHIDE MIHASHI、TATSUO YAMAUCHI

  DOI：10.1248/cpb.35.553

  日期：——

  From the dried herb of Actinostemma lobatum MAXIM. (Cucurbitaceae), four dammarane-type triterpene glycosides named actinostemmosides A, B, C and D were isolated and their structures were elucidated on the basis of chemical and spectral evidence. Actinostemmosides A, B and C were identified as 20-Ο-β-D-glucopyranosides of 3β, 6α, 20, 27-tetrahydroxy- (20S) -dammar-24-ene, 3β, 7β, 20, 27-tetrahydroxy- (20S) -dammar-24-ene and 3β, 7β, 18, 20, 27-pentahydroxy- (20S) -dammar-24-ene, respectively, and actinostemmoside D, as the α-L-rhamnopyranosyl- (1→2) -β-D-glucopyranoside of 3β, 6α, 20, 27-tetrahydroxy- (20R) -dammar-24-ene.

  为Actinostemma lobatum MAXIM 的干燥草本。 （葫芦科）分离了四种达玛烷型三萜糖苷，分别命名为放线菊苷 A、B、C 和 D，并根据化学和光谱证据阐明了它们的结构。 Actinostemmosides A、B 和 C 被鉴定为 3β, 6α, 20, 27-四羟基- (20S) -dammar-24-ene, 3β, 7β, 20, 27-四羟基- ( 20S) -dammar-24-ene 和 3β, 7β, 18, 20, 27-五羟基- (20S) -dammar-24-ene 分别，以及放线菌苷 D，作为 α-L-吡喃鼠李糖基- (1→2) 3β,6α,20,27-四羟基-(20R)-dammar-24-ene的-β-D-吡喃葡萄糖苷。