10,15-Dicyclopropylidentrispiro<3.1.3.1.3.1>pentadecan-5-on | 89560-57-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 10,15-Dicyclopropylidentrispiro<3.1.3.1.3.1>pentadecan-5-on
• 英文别名: 5,15-di(cyclopropylidene)trispiro[3.1.36.1.311.14]pentadecan-10-one
• CAS: 89560-57-6
• 化学式: C₂₁H₂₆O
• 分子量: 294.437
• InChiKey: PHSWWAPPZWIZBL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.26
• 重原子数：
  22.0
• 可旋转键数：
  0.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.76
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  10,15-Dicyclopropylidentrispiro<3.1.3.1.3.1>pentadecan-5-on 在 potassium tert-butylate 、 potassium carbonate 作用下， 以 水 、 二甲基亚砜 、 丙酮 为溶剂， 反应 20.0h， 生成 1-<<1-(cyclobutylidene-cyclopropyl-methyl)cyclobutyl>-cyclopropylidene-methyl>-cyclobutane-carboxylic acid ethyl ester
  参考文献：
  名称：

  Towards acyclic 1,1-linked polycyclobutanes as potential precursors of polyspiranes with a helical primary structure: Synthesis of tercyclobutanes and attempted synthesis of quinquecyclobutanes

  摘要：

  Acyclic 1,1-linked polycyclobutanes 1 should be potentially prone to rearrange to polyspiranes with a helical primary structure. In an exploratory study, the synthesis of die tercyclobutanes 8 (5-6-7-8) and 15 (9-10-11-12-16-15 or 14-15), and several approaches to quinquecyclobutanes with the beta- and delta-ketoesters 35 (15-33-34-35) and 24b (23-24a-24b). respectively, as most promising precursors are described. (C) 1999 Elsevier Science Ltd. Ail rights reserved.

  DOI：

  10.1016/s0040-4020(99)00098-8
• 作为产物：
  描述：

  triphenylphosphonium cyclopropylide 、 trimethyleneketene trimer 以 苯 为溶剂， 反应 20.0h， 以50%的产率得到10,15-Dicyclopropylidentrispiro<3.1.3.1.3.1>pentadecan-5-on
  参考文献：
  名称：

  Towards [6.5]coronane - fivefold cyclobutylmethyl-cyclopentyl rearrangement in a pentaspiroheneicosanal

  摘要：

  DOI：

  10.1016/s0040-4039(00)87866-1

文献信息

• FITJER, L.;GIERSIG, M.;CLEGG, W.;SCHORMANN, N.;SHELDRICK, G. M., TETRAHEDRON LETT., 1983, 24, N 48, 5351-5354
  作者：FITJER, L.、GIERSIG, M.、CLEGG, W.、SCHORMANN, N.、SHELDRICK, G. M.

  DOI：——

  日期：——
• GIERSIG, MANFRED;WEHLE, DETLEF;FITJER, LUTZ;SCHORMANN, NORBERT;CLEGG, WIL+, CHEM. BER., 121,(1988) N 3, 525-531
  作者：GIERSIG, MANFRED、WEHLE, DETLEF、FITJER, LUTZ、SCHORMANN, NORBERT、CLEGG, WIL+

  DOI：——

  日期：——
• Giersig, Manfred; Wehle, Detlef; Fitjer, Lutz, Chemische Berichte, 1988, vol. 121, p. 525 - 532
  作者：Giersig, Manfred、Wehle, Detlef、Fitjer, Lutz、Schormann, Norbert、Clegg, William

  DOI：——

  日期：——
• Towards acyclic 1,1-linked polycyclobutanes as potential precursors of polyspiranes with a helical primary structure: Synthesis of tercyclobutanes and attempted synthesis of quinquecyclobutanes
  作者：Said Gaini-Rahimi、Christoph Steeneck、Imelda Meyer、Lutz Fitjer、Frank Pauer、Mathias Noltemeyer

  DOI：10.1016/s0040-4020(99)00098-8

  日期：1999.3

  Acyclic 1,1-linked polycyclobutanes 1 should be potentially prone to rearrange to polyspiranes with a helical primary structure. In an exploratory study, the synthesis of die tercyclobutanes 8 (5-6-7-8) and 15 (9-10-11-12-16-15 or 14-15), and several approaches to quinquecyclobutanes with the beta- and delta-ketoesters 35 (15-33-34-35) and 24b (23-24a-24b). respectively, as most promising precursors are described. (C) 1999 Elsevier Science Ltd. Ail rights reserved.
• Towards [6.5]coronane - fivefold cyclobutylmethyl-cyclopentyl rearrangement in a pentaspiroheneicosanal
  作者：Lutz Fitjer、Manfred Giersig、William Clegg、Norbert Schormann、George M. Sheldrick

  DOI：10.1016/s0040-4039(00)87866-1

  日期：——