4-isopropyl-N-(5-methylpyridin-2-yl)benzamide | 560078-06-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 4-isopropyl-N-(5-methylpyridin-2-yl)benzamide
• 英文别名: N-(5-methylpyridin-2-yl)-4-propan-2-ylbenzamide
• CAS: 560078-06-0
• 化学式: C₁₆H₁₈N₂O
• mdl: MFCD03385735
• 分子量: 254.332
• InChiKey: ATASETIYIOOZLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] COMPOUNDS THAT EXPAND HEMATOPOIETIC STEM CELLS<br/>[FR] COMPOSÉS QUI DÉVELOPPENT DES CELLULES SOUCHES HÉMATOPOÏÉTIQUES
  申请人：IRM LLC

  公开号：WO2012102937A2

  公开（公告）日：2012-08-02

  The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.