dipotassium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxylato-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: dipotassium;(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxylato-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate
• 化学式: C42H60K2O16
• 分子量: 899.1
• InChiKey: BIVBRWYINDPWKA-VLQRKCJKSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -6.42
• 重原子数：
  60
• 可旋转键数：
  5
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  273
• 氢给体数：
  6
• 氢受体数：
  16

文献信息

• Topical composition and use thereof for the prophylaxis and the treatment of defects connected to inflammatory dermopathies
  申请人：Skinius S.R.L.

  公开号：EP2387990A1

  公开（公告）日：2011-11-23

  The invention refers to a topical composition and to its use for the prophylaxis and the treatment of defects connected to inflammatory dermopathies. Particularly, the invention pertains to a topical composition comprising at least an alum, 18-β-glycyrrhetic acid and/or one derivative thereof, and vitamin A and/or one derivative thereof, and the use of such composition for the prophylaxis and the treatment of inflammatory dermopathies, preferably of the seborrhoeic dermatitis and of those affections in which the presence of an excess of sebum occurs.

  本发明涉及一种外用组合物及其用于预防和治疗与炎症性皮肤病有关的缺陷的用途。特别是，本发明涉及一种外用组合物，该组合物至少包含明矾、18-β-甘草亭酸和/或其衍生物，以及维生素 A 和/或其衍生物，该组合物还可用于预防和治疗炎症性皮肤病，尤其是脂溢性皮炎和皮脂过多的皮肤病。
• Plant extracts for the treatment and prevention of infections
  申请人：Rozenblat Sharon

  公开号：US10226499B2

  公开（公告）日：2019-03-12

  A composition comprising a Sanguisorbae officinalis plant extract and at least one additional plant extract selected from the group consisting of an Ailanthus altissima plant extract, a Galla rhois gallnut plant extract, a Glycyrrhiza Glabra plant extract, a Rheum palmatum plant extract and a Scutellaria baicalensis plant extract is disclosed. Compositions comprising Ailanthus altissima plant extract or Ailanthone are also disclosed.

  本发明公开了一种组合物，该组合物由 Sanguisorbae officinalis 植物提取物和至少另外一种选自 Ailanthus altissima 植物提取物、Galla rhois gallnut 植物提取物、Glycyrrhiza Glabra 植物提取物、Rheum palmatum 植物提取物和 Scutellaria baicalensis 植物提取物的植物提取物组成。还公开了包含 Ailanthus altissima 植物提取物或 Ailanthone 的组合物。
• Synergistic herbal compositions with prebiotic properties for treatment of skin infections, allergies and inflammation
  申请人：KAMEDIS LTD.

  公开号：US10967031B2

  公开（公告）日：2021-04-06

  Disclosed is a method of treating and/or preventing atopic dermatitis (AD) in a subject in need thereof, wherein the method comprises administering to the subject a therapeutically effective amount of a composition comprising a Sanguisorba officinalis root extract, an Ailanthus altissima bark extract, a Rheum palmatum root extract, a Cnidium monnieri fruit extract, a Scutellaria baicalensis root extract, and Glycyrrhiza glabra root extract thereby treating and/or preventing AD in the subject.

  公开了一种治疗和/或预防有需要的受试者特应性皮炎（AD）的方法，其中该方法包括向受试者施用治疗有效量的组合物，该组合物包含山银花根提取物、艾兰树皮提取物、大黄根提取物、蛇床子果提取物、黄芩根提取物和甘草根提取物，从而治疗和/或预防受试者的特应性皮炎。
• PERFLUOROCARBON EYE CREAM FORMULATIONS
  申请人：Oxygen Biotherapeutics, Inc.

  公开号：EP2547201A1

  公开（公告）日：2013-01-23
• TOPICAL COMPOSITION AND USE THEREOF FOR THE PROPHYLAXIS AND THE TREATMENT OF DEFECTS CONNECTED TO INFLAMMATORY DERMOPATHIES
  申请人：Skinius S.R.L.

  公开号：EP2566455B1

  公开（公告）日：2018-09-12