L-瓜氨酸-DL-苹果酸 | 70796-17-7

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 其他氨基酸衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: L-瓜氨酸-DL-苹果酸
• 中文别名: 瓜氨酸苹果酸盐；L-瓜氨酸DL-苹果酸盐
• 英文名称: Citrulline malate
• 英文别名: (2S)-2-amino-5-(carbamoylamino)pentanoic acid;2-hydroxybutanedioic acid
• CAS: 70796-17-7
• 化学式: C10H19N3O8
• 分子量: 309.27
• InChiKey: DROVUXYZTXCEBX-WCCKRBBISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.25
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  213
• 氢给体数：
  7
• 氢受体数：
  9

安全信息

• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H315,H319,H335

文献信息

• ACTIVITY-ENHANCING SUPPLEMENT
  申请人：Richardson Joseph

  公开号：US20180000147A1

  公开（公告）日：2018-01-04

  An activity-enhancing supplement can include niacin and at least two ingredients selected from citrulline, agmatine, an endurance enhancer, a counteracting agent, a nitrogen-containing compound, a muscle building component, branched chain amino acid, and combinations thereof.

  增强活动的补充剂可以包括烟酸和至少两种成分，选自瓜氨酸、精氨酸、耐力增强剂、对抗剂、含氮化合物、肌肉建设成分、支链氨基酸及其组合。
• PROTEIN BEVERAGE AND METHOD OF MAKING THE SAME
  申请人：Sherwood Shawn

  公开号：US20070148305A1

  公开（公告）日：2007-06-28

  An improved protein beverage/drink composition which may provide a relatively high protein content, ranging from about 0.01% by weight to about 15% by weight, while optionally employing a carbonation concentration between about 0.1 volumes of carbonation (per volume of liquid drink solution or liquid drink suspension) to about 6 volumes of carbonation. Preferably the protein is a protein, such preferably as whey protein, or others. The protein beverage may contain juice and/or an additive which provides energy generation enhancement. The protein beverage may be heat treated to inactivate pathogenic microbes in the presence of the carbonation which may be used to provide taste and mouth feel for the drink. Typically, the treatment for pathogenic microbe inactivation is carried out in the individual package used for storage and handling of the protein drink.

  一种改进的蛋白饮料/饮品配方，可提供相对较高的蛋白质含量，范围从约0.01%重量到约15%重量，同时可选择使用约0.1体积碳酸化浓度至约6体积碳酸化。最好的蛋白质是蛋白质，例如乳清蛋白或其他蛋白质。蛋白饮料可以含有果汁和/或提供能量增强的添加剂。蛋白质饮料可以经过热处理，在碳酸化的情况下灭活致病微生物，这可用于提供饮料的口感和口感。通常，在用于存储和处理蛋白质饮料的个别包装中进行致病微生物灭活处理。
• AGENT FOR PREVENTING OR AMELIORATING VASCULAR ENDOTHELIAL MALFUNCTION
  申请人：Kyowa Hakko Bio Co., Ltd.

  公开号：EP2815760A1

  公开（公告）日：2014-12-24

  An agent for preventing or ameliorating vascular endothelial malfunction and arteriosclerosis-related symptoms caused by the progress of vascular endothelial malfunction (e.g., ischemic diseases such as myocardial infarction, angina, and peripheral artery occlusion) or low blood flow-related symptoms (e.g., stiff shoulders, excessive sensitivity to cold, swelling, erectile dysfunction, rough skin and decrease in exercise performance due to skeletal muscle hypoactivity), which has an improved NO production enhancing effect is provided. A NO production enhancer comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients. An agent for preventing or ameliorating vascular endothelial malfunction, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients. An agent for preventing or ameliorating a symptom caused by vascular endothelial malfunction, comprising citrulline or a salt thereof and glutathione or a salt thereof as active ingredients.

  一种用于预防或改善因血管内皮功能失调（如心肌梗塞、心绞痛和外周动脉闭塞等缺血性疾病）或低血流量相关症状（如肩膀僵硬、对冷过度敏感、浮肿、勃起功能障碍和因骨骼肌活性低下导致的运动能力下降）的进展而引起的血管内皮功能失调和动脉硬化相关症状的制剂、本研究提供了一种具有改善 NO 生成增强效果的 NO 生成增强剂。一种由瓜氨酸或其盐和谷胱甘肽或其盐作为活性成分组成的 NO 生成促进剂。一种预防或改善血管内皮功能失调的制剂，包含瓜氨酸或其盐和谷胱甘肽或其盐作为活性成分。一种预防或改善由血管内皮功能失调引起的症状的制剂，其活性成分包括瓜氨酸或其盐和谷胱甘肽或其盐。
• USE OF LECITHINS AS A BIOCIDE AGAINST ARTHROPODS
  申请人：Martin Bretones, Germán

  公开号：EP3639666A1

  公开（公告）日：2020-04-22

  The present invention refers to the use of a lecithin as a biocide against arthropod species; wherein the lecithin is applied in the form of a liquid composition; it also refers to said liquid which comprises a solid formula of powder lecithin and water; as well as said formulation.

  本发明是指使用卵磷脂作为杀灭节肢动物的杀菌剂；其中卵磷脂以液体组合物的形式使用；本发明还指由粉末卵磷脂和水的固体配方组成的液体；以及所述配方。
• DRY COMPOSITION FOR DISSOLVING IN WATER
  申请人：Biogliko Spolka Z Ograniczona Odpowiedzialnoscia

  公开号：EP3991720A1

  公开（公告）日：2022-05-04

  The subject of invention is a dry composition for dissolving in water containing an osmotic agent, characterised in that it comprises glucose, one or more sugar alcohols and one or more mucoprotectants, for use as supportive product for the organism of a patient preparing for endoscopy, wherein aqueous solution of the composition is a clear solution of osmolarity of > 170 mOsm/L.

  本发明的主题是一种可溶于水的含有渗透剂的干燥组合物，其特征在于它由葡萄糖、一种或多种糖醇和一种或多种粘液保护剂组成，可用作准备进行内窥镜检查的患者机体的辅助产品，其中组合物的水溶液是渗透压大于 170 mOsm/L 的透明溶液。