1-Aethyl-cyclopentanon-(5)-dicarbonsaeure-(2,3) | 15235-86-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 1-Aethyl-cyclopentanon-(5)-dicarbonsaeure-(2,3)
• 英文别名: 1,2-Cyclopentanedicarboxylicacid, 3-ethyl-4-oxo-；3-ethyl-4-oxocyclopentane-1,2-dicarboxylic acid
• CAS: 15235-86-6
• 化学式: C₉H₁₂O₅
• 分子量: 200.191
• InChiKey: VDTUXLYZCFAPOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  91.7
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• COMPOUNDS THAT MODULATE AUTOIMMUNITY AND METHODS OF USING THE SAME
  申请人：Eisenbarth George

  公开号：US20120195929A1

  公开（公告）日：2012-08-02

  The invention provides methods of preventing, treating or ameliorating autoimmune diseases such as diabetes by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of small organic compounds. The invention also provides pharmaceutical compositions comprising the therapeutically effective small organic compounds and methods of using the same.
• [EN] COMPOUNDS THAT MODULATE AUTOIMMUNITY AND METHODS OF USING THE SAME<br/>[FR] COMPOSÉS QUI MODULENT L'AUTO-IMMUNITÉ ET PROCÉDÉS POUR LES UTILISER
  申请人：UNIV COLORADO

  公开号：WO2010141883A1

  公开（公告）日：2010-12-09

  The invention provides methods of preventing, treating or ameliorating autoimmune diseases such as diabetes by modulating the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of small organic compounds. The invention also provides pharmaceutical compositions comprising the therapeutically effective small organic compounds and methods of using the same.