N,N-二乙基甘氨酸钠 | 5426-55-1

• 物质功能分类: 生物化工 - 氨基酸及其衍生物 - 甘氨酸类衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N,N-二乙基甘氨酸钠
• 中文别名: N,N-二乙基甘氨酸钠盐
• CAS: 5426-55-1
• 化学式: C6H13NNaO2
• 分子量: 154.16
• InChiKey: XZQDOIKSUNQDGV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.03
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  40.5
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 安全说明：
  S24/25
• 海关编码：
  2922499990

文献信息

• 2-[1H-Benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides as kinase inhibitors
  申请人：Aurrecoechea Natalia

  公开号：US20100081653A1

  公开（公告）日：2010-04-01

  2-[1H-benzimidazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and 2-[benzothiazol-2(3H)-ylidene]-2-(pyrimidin-2-yl)acetamides and their salts are kinase inhibitors, useful in the treatment of cancer.

  2-[1H-苯并咪唑-2(3H)-基]-2-(嘧啶-2-基)乙酰胺和2-[苯并噻唑-2(3H)-基]-2-(嘧啶-2-基)乙酰胺及其盐是激酶抑制剂，在癌症治疗中有用。
• Hair cosmetic, aminocarboxylic acid amide and method for producing the same
  申请人：Kao Corporation

  公开号：US20030035784A1

  公开（公告）日：2003-02-20

  A hair cosmetic which can impart, to hairs, flexibility, smoothness and oily feeling when the hairs are wetted and smoothness, softness and combing easiness after the hairs are dried are provided, the hair cosmetic comprising an amine represented by the formula (I): Formula (I) 1 (wherein R 1 represents a C 8-40 alkyl group or alkenyl group or a group represented by the formula R 5 O—(AO) n —C m H 2m — (R 5 represents a C 8-40 alkyl group or alkenyl group having 8 to 40 carbon atoms, A represents a C 2-3 alkylene group, n denotes a number from 0 to 30 in average and m denotes an integer of 2 or 3), R 2 represents a C 1-5 alkylene group, R 3 represents H, a C 1-24 alkyl group, alkenyl group or hydroxyalkyl group or a C 6-28 aryl group or arylalkyl group, R 4 represents H, a C 1-5 alkyl group, alkylene group or hydroxyalkyl group or a C 6-28 aryl group or arylalkyl group, p denotes an integer from 1 to 3, q and r denote integers from 0 to 2 and p+q+r is equal to 3. Also, the amine (I) can be produced with high selectivity and highly economically by reacting a primary amine with an aminocarboxylic acid to run amidation. An amine represented by the formula (1), its salt or quaternary ammonium salt are also provided: Formula (1) 2

  提供一种头发化妆品，它可以在头发被浸湿时赋予头发柔软、光滑和油腻的感觉，并在头发干燥后提供光滑、柔软和易于梳理的效果。该头发化妆品包括一种由式(I)表示的胺：式(I)1（其中，R1表示C8-40烷基或烯基或由式R5O-（AO）n-CmH2m-表示的基团（其中，R5表示具有8至40个碳原子的C8-40烷基或烯基，A表示C2-3烷基，n表示平均值为0至30的数字，m表示2或3的整数），R2表示C1-5烷基，R3表示H、C1-24烷基、烯基或羟基烷基或C6-28芳基基团或芳基烷基基团，R4表示H、C1-5烷基、烷基或羟基烷基或C6-28芳基基团或芳基烷基基团，p表示1至3的整数，q和r表示0至2的整数，且p+q+r等于3。此外，胺（I）可以通过将一种一级胺与一种氨基羧酸反应以进行酰胺化，从而高选择性、高经济性地生产。还提供一种由式（1）表示的胺、其盐或季铵盐：式（1）2。
• Highly concentrated aqueous solutions of n,n-dialkyl-glycines and process for preparation thereof
  申请人：——

  公开号：US20040238786A1

  公开（公告）日：2004-12-02

  An aqueous high-concentration solution of N,N-dialkylglycine, economical, easy to handle, and useful for subsequent organic chemical reactions, is provided. Also is provided a process for production thereof. The aqueous high-concentration solution of N,N-dialkylglycine which contains the N,N-dialkylglycine at a concentration of 30-80% by mass, and a metal-mineral acid salt at a content of 0.3-3% by mass can be produced industrially from an aqueous N,N-dialkylglycine alkali metal salt as the source material by the steps of (i) neutralizing an aqueous solution of an N,N-dialkylglycine alkali metal salt with a mineral acid, (ii) condensing the obtained aqueous solution by removal of water, and (iii) separating by solid-liquid separation the deposited alkali metal-mineral acid salt from the resulting slurry of the aqueous N,N-dialkylglycine solution and the alkali metal-mineral acid salt.

  提供了一种水溶性高浓度的N,N-二烷基甘氨酸溶液，经济实用，易于操作，并可用于随后的有机化学反应。同时提供了其生产工艺。该水溶性高浓度的N,N-二烷基甘氨酸溶液含有30-80%的N,N-二烷基甘氨酸质量浓度和0.3-3%的金属-矿物酸盐含量，可以从水溶性N,N-二烷基甘氨酸碱金属盐作为原料进行工业生产，其步骤包括(i)用矿物酸中和水溶性N,N-二烷基甘氨酸碱金属盐的水溶液，(ii)通过去除水来浓缩所得的水溶液，(iii)将沉淀的碱金属-矿物酸盐从所得的水溶性N,N-二烷基甘氨酸溶液和碱金属-矿物酸盐的混合物中通过固液分离分离出来。
• BCRP/ABCG2 INHIBITOR
  申请人：Yamazaki Ryuta

  公开号：US20090253656A1

  公开（公告）日：2009-10-08

  The present invention is directed to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. The BCRP inhibitor contains, as an active ingredient, an acrylonitrile derivative represented by formula (1): wherein one of R 1 and R 2 represents a cyano group and the other represents a hydrogen atom; Ar 1 represents a group selected from among the groups represented by formulas (2) to (4): and Ar 2 represents an aromatic hydrocarbon group having a condensed ring which may be substituted by a halogen atom, or a group selected from among the groups represented by the following formulas (5) to (15): or a salt thereof.

  该发明涉及一种乳腺癌耐药蛋白（BCRP/ABCG2）抑制剂。该BCRP抑制剂包含以下化合物作为活性成分，其化学式为（1）：其中R1和R2中的一个代表氰基，另一个代表氢原子；Ar1代表从以下化学式（2）至（4）中选出的一种基团：Ar2代表一种含有可能被卤素原子取代的融合环的芳香烃基团，或者从以下化学式（5）至（15）中选出的一种基团：或其盐。
• Emulsion ink for stencil printing
  申请人：RISO KAGAKU CORPORATION

  公开号：EP0846737A1

  公开（公告）日：1998-06-10

  A W/O emulsion ink, which is superior in emulsion stability, causes no softening or separation even after stored for a long time, and can always provide prints of uniform quality, is provided. The emulsion ink has an oil phase and a water phase, in which said water phase has a pH of 6.0 to 12.0, preferably 7.0 to 9.0 at 23 °C. The emulsion ink may contain a water-insoluble colorant in the water phase and/or the oil phase. Preferably, the water phase has a pH buffer action.

  本发明提供了一种 W/O 型乳液油墨，它具有卓越的乳液稳定性，即使存放很长时间也不会软化或分离，并能始终提供质量均匀的印刷品。这种乳剂油墨具有油相和水相，其中水相在 23 °C 时的 pH 值为 6.0 至 12.0，最好为 7.0 至 9.0。乳液墨水的水相和/或油相中可能含有水不溶性着色剂。水相最好具有 pH 缓冲作用。