3-Benzoyl-2-(4-methylphenyl)-5-phenylcyclopenta-2,4-diene-1,1-dicarbonitrile | 1010795-17-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 英文名称: 3-Benzoyl-2-(4-methylphenyl)-5-phenylcyclopenta-2,4-diene-1,1-dicarbonitrile
• CAS: 1010795-17-1
• 化学式: C₂₇H₁₈N₂O
• 分子量: 386.453
• InChiKey: AQWHYXHWQNYWJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  30
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-(4-甲基亚苄基)-丙二腈 、 二苯甲酰基乙炔 在 三苯基膦 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 以72%的产率得到3-Benzoyl-2-(4-methylphenyl)-5-phenylcyclopenta-2,4-diene-1,1-dicarbonitrile
  参考文献：
  名称：

  Reaction between triphenylphosphine, diaroylacetylenes and arylidenemalononitriles: a novel and simple synthesis of 3-aroyl-2,5-diaryl-2,4-cyclopentadiene-1,1-dicarbonitriles

  摘要：

  A novel and simple synthesis of 3-aroyl-2,5-diaryl-2,4-cyclopentadiene-1,1-dicarbonitriles is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of triphenylphosphine to diaroylacetylenes, was trapped by arylidenemalononitriles to produce the title compounds under mild reaction conditions in fairly good yields. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.12.018

文献信息

• Reaction between triphenylphosphine, diaroylacetylenes and arylidenemalononitriles: a novel and simple synthesis of 3-aroyl-2,5-diaryl-2,4-cyclopentadiene-1,1-dicarbonitriles
  作者：Mehdi Adib、Mohammad Hosein Sayahi、Shabnam Mahernia、Long-Guan Zhu

  DOI：10.1016/j.tetlet.2007.12.018

  日期：2008.2

  A novel and simple synthesis of 3-aroyl-2,5-diaryl-2,4-cyclopentadiene-1,1-dicarbonitriles is described. The reactive 1:1 zwitterionic intermediate, formed by the addition of triphenylphosphine to diaroylacetylenes, was trapped by arylidenemalononitriles to produce the title compounds under mild reaction conditions in fairly good yields. (c) 2007 Elsevier Ltd. All rights reserved.