N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺 | 333352-59-3

• 物质功能分类: 生物化工 - 生化试剂 - 激动剂抑制剂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-(4-溴苯基)-N'-(2,2,6,6-四甲基哌啶-4-基)草酰胺
• 英文名称: N-(4-Bromophenyl)-N'-(2,2,6,6-Tetramethylpiperidin-4-Yl)ethanediamide
• 英文别名: N'-(4-bromophenyl)-N-(2,2,6,6-tetramethylpiperidin-4-yl)oxamide
• CAS: 333352-59-3
• 化学式: C₁₇H₂₄BrN₃O₂
• 分子量: 382.3
• InChiKey: QQRFLGRIDNNARB-UHFFFAOYSA-N

物化性质

• 密度：
  1.35
• 溶解度：
  DMSO：10 mg/mL（26.16 mM；需要超声）

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  70.2
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• Novel Compositions for Inhibiting Virus Entry and Promoting Virolysis, and Methods Thereof
  申请人：Chaiken Irwin

  公开号：US20140050793A1

  公开（公告）日：2014-02-20

  The present invention includes a composition comprising a gold nanoparticle complexed with a cysteine-containing peptide. The invention also includes the method of preparing a composition comprising a gold nanoparticle complexed with a cysteine-containing peptide. The invention further includes a method of causing virolysis of a virus using the compositions described therein.
• US9114107B2
  申请人：——

  公开号：US9114107B2

  公开（公告）日：2015-08-25
• [EN] NOVEL COMPOSITIONS FOR INHIBITING VIRUS ENTRY AND PROMOTING VIROLYISIS, AND METHODS THEREOF<br/>[FR] NOUVELLES COMPOSITIONS POUR INHIBER L'ENTRÉE DE VIRUS ET PROMOTION DE LA VIROLYSE, ET PROCÉDÉS POUR CELLES-CI
  申请人：UNIV DREXEL

  公开号：WO2012048033A2

  公开（公告）日：2012-04-12

  The present invention includes a composition comprising a gold nanoparticle compiexed with a cysteine-containing compound. The invention also includes the method of preparing a composition comprising a gold nanoparticle compiexed with a cysteine-containing compound. The invention ftirther includes a method of causing virolysis of a virus using the compositions described therein. The invention ftirther includes a method of inhibiting vims entry using the compositions described therein.