foliol | 37720-78-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: foliol
• 英文别名: (1R,2S,4S,5S,6R,9S,10S,13R)-5-(hydroxymethyl)-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-2,6-diol
• CAS: 37720-78-8
• 化学式: C₂₀H₃₂O₃
• 分子量: 320.472
• InChiKey: ZHAIQJLGKAVXSD-SSADKFRXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  foliol 、 N,N-二甲基甲酰胺二甲基缩醛 、 碘甲烷 生成 [(1R,2S,4S,5R,6R,9R,10S,13R)-2-formyloxy-6-hydroxy-5,9-dimethyl-14-methylidene-5-tetracyclo[11.2.1.01,10.04,9]hexadecanyl]methyl formate
  参考文献：
  名称：

  ACKLAND, MARK J.;GORDON, JOHN F.;HANSON, JAMES R.;YEOH, BOON LENG;RATCLIF+, J. CHEM. SOC. PERKIN TRANS. PT 1,(1988) N 7, C. 2013-2017

  摘要：

  DOI：

文献信息

• ALOE VERA EXTRACT, PROCESS FOR PRODUCTION OF ALOE VERA EXTRACT, AND AMELIORATING AGENT FOR HYPERGLYCEMIA
  申请人：MORINAGA MILK INDUSTRY CO., LTD.

  公开号：EP1952817A1

  公开（公告）日：2008-08-06

  The present invention provides: an Aloe vera extract that can be safely ingested, can be used as a material of food for preventing lifestyle diseases, contains an extremely low level of an anthraquinone (anthraquinone-based compound), and can be added to foods; and a method of producing the Aloe vera extract. A supercritical fluid extraction method can produce an Aloe vera extract containing a mixture that consists of a cyclolanostane compound and a lophenol compound in an amount of 1.0% by mass or more and having the following properties (1) and/or (2): (1) the mass mixing ratio of the cyclolanostane compound and lophenol compound is as follows: cyclolanostane compound : lophenol compound = 6.3 : 2.7 to 5.1 : 4.9; and/or (2) the content of an anthraquinone-based compound is 0.001% by mass or less.

  本发明提供了：一种可安全摄入、可用作预防生活习惯病的食品原料、含有极低水平的蒽醌（蒽醌类化合物）、可添加到食品中的芦荟提取物；以及一种芦荟提取物的生产方法。超临界流体萃取法可以生产出一种芦荟提取物，该提取物含有一种由环羊毛甾烷化合物和洛酚化合物组成的混合物，其质量分数为 1.0% 或以上，并具有以下特性（1）和/或（2）： (1) 环羊毛甾烷化合物和洛酚化合物的质量混合比如下： 环羊毛甾化合物：氯酚化合物 = 6.3 : 2.7 至 5.1 ：4.9；和/或 (2) 蒽醌类化合物的含量为 0.001%（质量百分比）或以下。
• Aloe vera extract, method of producing aloe vera extract, and hyperglycemia improving agent
  申请人：Morinaga Milk Industry Co., Ltd.

  公开号：EP2206509A1

  公开（公告）日：2010-07-14

  A method of producing an Aloe vera extract comprising: preparing powdery Aloe vera mesophyll by removing water from a mesophyll part excluding leaf skin of Aloe vera by freeze-drying or hot-air drying; and extracting an Aloe vera extract from the resultant powdery Aloe vera mesophyll by a supercritical fluid extraction method based on the following conditions (a) to (e): (a) the extraction solvent is carbon dioxide; (b) the extraction temperature is 50 to 69°C; (c) the pressure is 15 to 60 MPa; (d) no entrainer is used; and (e) the extraction time is 50 to 70 minutes.

  一种芦荟提取物的生产方法，包括：通过冷冻干燥或热风干燥去除芦荟叶皮以外的中叶部分的水分，制备粉末状芦荟中叶；通过基于以下条件(a)至(e)的超临界流体萃取法，从得到的粉末状芦荟中叶中提取芦荟提取物： (a) 萃取溶剂为二氧化碳； (b) 萃取温度为 50 至 69°C (c) 压力为 15 至 60 兆帕； (d) 不使用夹带器；以及 (e) 萃取时间为 50 至 70 分钟。
• ACKLAND, MARK J.;GORDON, JOHN F.;HANSON, JAMES R.;YEOH, BOON LENG;RATCLIF+, J. CHEM. SOC. PERKIN TRANS. PT 1,(1988) N 7, C. 2013-2017
  作者：ACKLAND, MARK J.、GORDON, JOHN F.、HANSON, JAMES R.、YEOH, BOON LENG、RATCLIF+

  DOI：——

  日期：——
• PROCESS FOR THE PRODUCTION OF FINE CHEMICALS
  申请人：Metanomics GmbH

  公开号：EP1871883A1

  公开（公告）日：2008-01-02
• ALOE VERA EXTRACT, METHOD OF PRODUCING ALOE VERA EXTRACT, AND HYPERGLYCEMIA IMPROVING AGENT
  申请人：MORINAGA MILK INDUSTRY CO., LTD.

  公开号：EP1952817B1

  公开（公告）日：2013-05-22