2-(4-Isopropyl-phenyl)-acetamidine | 885953-20-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(4-Isopropyl-phenyl)-acetamidine
• 英文别名: 2-(4-propan-2-ylphenyl)ethanimidamide
• CAS: 885953-20-8
• 化学式: C₁₁H₁₆N₂
• 分子量: 176.26
• InChiKey: RHWQBFAWGGPCGQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  49.9
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• AMIDINE SUBSTITUTED BETA-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS
  申请人：AiCuris GmbH & Co. KG

  公开号：US20170100379A1

  公开（公告）日：2017-04-13

  The present invention relates to novel β-lactam compounds, their preparation and use. In particular, this invention relates to novel β-lactam compounds which are amidine substituted monobactam derivatives useful as antimicrobial agents and their preparation.
• ANALOGUES OF PENTAMIDINE AND USES THEREFOR
  申请人：Auransa Inc.

  公开号：US20220144776A1

  公开（公告）日：2022-05-12

  The present disclosure provides a group of aromatic (e.g., pyridinyl, pyrimidinyl, pyrazinyl, or phenyl) diamidine analogs and pharmaceutically acceptable salts that are useful for treating a proliferative disease. The proliferative disease may include solid cancer or blood cancer. Compositions, methods of synthesizing the same and methods for treating various cancer using the analogs are disclosed herein. The present disclosure also provides pharmaceutical formulations comprising at least one of the compounds with a pharmaceutically acceptable carrier, diluent or excipient therefor.
• US9782390B2
  申请人：——

  公开号：US9782390B2

  公开（公告）日：2017-10-10