3-Amino-bornan | 35973-43-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3-Amino-bornan
• 英文别名: bornan-3-ylamine；Epibornylamin；3-Amino-1.7.7-trimethyl-bicyclo-[1.2.2]-heptan；3-Amino-camphan；4,7,7-Trimethylbicyclo[2.2.1]heptan-2-amine
• CAS: 35973-43-4
• 化学式: C₁₀H₁₉N
• 分子量: 153.268
• InChiKey: HXLBZMMJEVSVKA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 sodium 作用下， 生成 3-Amino-bornan
  参考文献：
  名称：

  Murayama; Arihara, Yakugaku Zasshi, 1927, p. 60

  摘要：

  DOI：

文献信息

• Thiazoles as inhibitors of 11B-hydroxysteroid dehydrogenase
  申请人：Gillespie Paul

  公开号：US20070167622A1

  公开（公告）日：2007-07-19

  Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.

  提供的化合物为公式(I)： 以及其中可接受的药用盐，其中取代基如说明书所述。这些化合物以及包含它们的药物组合物可用于治疗诸如2型糖尿病和代谢综合征等疾病。
• Aminopyrimidine Derivatives Inhibiting Protein Kinase Activity, Method For The Preparation Thereof And Pharmaceutical Composition Containing Same
  申请人：Park Boonsaeng

  公开号：US20090227612A1

  公开（公告）日：2009-09-10

  A compound of formula 1 efficiently inhibits several protein kinases including glycogen synthase kinase 3 (GSK), aurora kinase, extracellular signal-regulated kinase (ERK), protein kinase B (AKT), and the likes, to control signal transductions involved in variable disorders such as diabetes, obesity, dementia, cancer, and inflammation.

  化合物1的公式能有效抑制多种蛋白激酶，包括糖原合成酶激酶3（GSK）、极化激酶、细胞外信号调节激酶（ERK）、蛋白激酶B（AKT）等，以控制涉及不同疾病的信号转导，如糖尿病、肥胖、痴呆、癌症和炎症。
• Konowalow; Kikina, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1902, vol. 34, p. 935
  作者：Konowalow、Kikina

  DOI：——

  日期：——
• AMINOPYRIMIDINE DERIVATIVES INHIBITING PROTEIN KINASE ACTIVITY, METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
  申请人：Crystalgenomics, Inc.

  公开号：EP1973885A1

  公开（公告）日：2008-10-01
• Process for producing fluoroalkanesulfonamide derivatives
  申请人：Matsunaga Kei

  公开号：US20080058538A1

  公开（公告）日：2008-03-06

  There is provided a process for producing a fluoroalkanesulfonamide derivative represented by the formula [3], R 2 —NH—SO 2 —R f —R 1 [3] including reacting a fluoroalkanesulfonic anhydride represented by the formula [1], with an organic primary amine represented by the formula [2], in the presence of water and in the presence of a base selected from the group consisting of (a) a hydroxide of an alkali metal or alkaline-earth metal or (b) a basic salt containing an alkali metal or alkaline-earth metal.