2-(Dimethylamino)ethyl (2E)-(3-hydroxy-14-methyl-7-oxopodocarpan-13-ylidene)ethanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 2-(Dimethylamino)ethyl (2E)-(3-hydroxy-14-methyl-7-oxopodocarpan-13-ylidene)ethanoate
• 英文别名: 2-(dimethylamino)ethyl (2E)-2-(7-hydroxy-1,4b,8,8-tetramethyl-10-oxo-1,3,4,4a,5,6,7,8a,9,10a-decahydrophenanthren-2-ylidene)acetate
• 化学式: C₂₄H₃₉NO₄
• 分子量: 405.6
• InChiKey: GMHWATCMBXIANN-DTQAZKPQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  29
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Animal growth control
  申请人：Naylor, Graham John

  公开号：EP0051964A2

  公开（公告）日：1982-05-19

  This invention relates to a method of improving food conversion efficiency in a non-human animal comprising administering to said animal a food-conversion improving effective amount of vanadium and/or another NaKATPase enzyme inhibitor and to an animal feedstuff for use in such a method, which feedstuff contains at least 1 p.p.m. of vanadium.

  本发明涉及一种提高非人类动物食物转化效率的方法，包括向所述动物施用有效量的钒和/或另一种NaKATPase酶抑制剂，以及用于这种方法的动物饲料，该饲料含有至少1 p.p.m.的钒。
• Tricyclic rantes receptor ligands
  申请人：——

  公开号：US20030092674A1

  公开（公告）日：2003-05-15

  In various aspects, the invention provides compounds that bind to one or more RANTES receptors for the treatment of chemokine mediated disease states, such as compounds of formula (I): 1

  在各个方面，本发明提供了与一种或多种 RANTES 受体结合的化合物，用于治疗趋化因子介导的疾病状态，如式 (I) 化合物： 1
• COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF
  申请人：UNIVERSITY OF NEBRASKA BOARD OF REGENTS

  公开号：EP1005324B1

  公开（公告）日：2005-03-30
• EP1005324A4
  申请人：——

  公开号：EP1005324A4

  公开（公告）日：2001-06-06
• Compounds exhibiting efflux inhibitor activity and composition and uses thereof
  申请人：Wempe Fitzpatrick Michael

  公开号：US20070254859A1

  公开（公告）日：2007-11-01

  At least one compound chosen from compounds of Formula I: a pharmaceutically acceptable salt or ester thereof, a solvate thereof, a chelate thereof, a non-covalent complex thereof, a prodrug thereof, and mixtures of any of the foregoing, wherein: n is a number from 1 to 900, wherein the individual units may be the same or different; W is chosen from alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; each of R 2 , R 3 , R 4 and R 5 is independently chosen from —H, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl; Z′ is chosen from —O—, —N—, —NO—, —NR 4 —, —S—, —SO— and —SO 2 —, wherein R 4 is defined as above; each of X, X′, Y and Z is independently chosen from —CR 4 R 5 —, —NH—, —NR 4 —, —NO—, —O—, —NOR 4 —, —S—, —SO—, —SO 2 —, wherein R 4 and R 5 are defined as above; R 1 is chosen from a tocopherol, a steroid and a flavonoid; and R 6 is chosen from any R 1 , alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, aralkyl and substituted aralkyl.