The subject invention concerns non-degradable three dimensional porous collagen scaffolds and coatings. These scaffolds can be prepared around sensors for implantation into a body. A specific embodiment of the invention concerns implantable glucose sensors. Sensors comprising a collagen scaffold of the invention have improved biocompatibility by minimizing tissue reactions while stimulating angiogenesis. The subject invention also concerns methods for preparing collagen scaffolds of the invention. The subject invention also concerns sensors that have a collagen scaffold of the invention around the exterior of the sensor.
                            本发明涉及不可降解的三维多孔胶原支架和涂层。这些支架可围绕传感器制备,以便植入人体。本发明的一个具体实施方案涉及植入式
葡萄糖传感器。由本发明胶原支架组成的传感器在刺激血管生成的同时最大限度地减少了组织反应,从而改善了
生物相容性。本发明还涉及制备本发明胶原支架的方法。本发明还涉及在传感器外部具有本发明胶原支架的传感器。