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    —— (7R)-N-(1,3-benzodioxol-5-yl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H27N3O4S
    (7R)-N-(1,3-benzodioxol-5-yl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-(3-chlorophenyl)-N-(2-methylphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C28H26ClN3OS
    (7S)-7-(3-chlorophenyl)-N-(2-methylphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7R)-N-(2-chloro-4-methylphenyl)-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C30H31ClN4OS
    (7R)-N-(2-chloro-4-methylphenyl)-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7R)-7-[4-(dimethylamino)phenyl]-N-[(3-methoxyphenyl)methyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C31H34N4O2S
    (7R)-7-[4-(dimethylamino)phenyl]-N-[(3-methoxyphenyl)methyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7R)-7-(3-chlorophenyl)-N-(2-phenylethyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H28ClN3OS
    (7R)-7-(3-chlorophenyl)-N-(2-phenylethyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-N-(furan-2-ylmethyl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C27H27N3O3S
    (7S)-N-(furan-2-ylmethyl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-[4-(dimethylamino)phenyl]-N-phenyl-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H30N4OS
    (7S)-7-[4-(dimethylamino)phenyl]-N-phenyl-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-N-(1,3-benzodioxol-5-yl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H27N3O4S
    (7S)-N-(1,3-benzodioxol-5-yl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-N-(3,5-dimethoxyphenyl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C30H31N3O4S
    (7S)-N-(3,5-dimethoxyphenyl)-7-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7R)-7-(3-chlorophenyl)-N-(2-methylphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C28H26ClN3OS
    (7R)-7-(3-chlorophenyl)-N-(2-methylphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7R)-7-[4-(dimethylamino)phenyl]-N-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C30H32N4O2S
    (7R)-7-[4-(dimethylamino)phenyl]-N-(3-methoxyphenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-(4-ethoxyphenyl)-N-(3-ethoxypropyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C28H35N3O3S
    (7S)-7-(4-ethoxyphenyl)-N-(3-ethoxypropyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— [(7E)-7-(4-bromobenzylidene)-3-(4-bromophenyl)-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl](2-chloro-5-nitrophenyl)methanone —— C27H20Br2ClN3O3
    [(7E)-7-(4-bromobenzylidene)-3-(4-bromophenyl)-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl](2-chloro-5-nitrophenyl)methanone
    —— 7-methyl-2-[(2-methylpropyl)amino]-3-[(Z)-(4-oxo-3-pentyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one —— C22H28N4O2S2
    7-methyl-2-[(2-methylpropyl)amino]-3-[(Z)-(4-oxo-3-pentyl-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]-4H-pyrido[1,2-a]pyrimidin-4-one
    —— 7,8-dimethyl-N-[3-[(3R)-3-methylpiperidin-1-yl]propyl]-4-oxo-[1,3]thiazino[3,2-a]benzimidazole-2-carboxamide —— C22H28N4O2S
    7,8-dimethyl-N-[3-[(3R)-3-methylpiperidin-1-yl]propyl]-4-oxo-[1,3]thiazino[3,2-a]benzimidazole-2-carboxamide
    —— 7,8-dimethyl-4-oxo-N-[(3S)-3-pyrrolidin-1-ylbutyl]-[1,3]thiazino[3,2-a]benzimidazole-2-carboxamide —— C21H26N4O2S
    7,8-dimethyl-4-oxo-N-[(3S)-3-pyrrolidin-1-ylbutyl]-[1,3]thiazino[3,2-a]benzimidazole-2-carboxamide
    —— (7-methyl-2-oxo-6-propan-2-ylchromen-4-yl)methyl (E)-3-(3-nitrophenyl)prop-2-enoate —— C23H21NO6
    (7-methyl-2-oxo-6-propan-2-ylchromen-4-yl)methyl (E)-3-(3-nitrophenyl)prop-2-enoate
    —— (7R)-1-(4-chlorophenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C22H15ClN2O2
    (7R)-1-(4-chlorophenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-7-(3,4-dimethoxyphenyl)-2,5-dioxo-1-(2,4,6-trimethylphenyl)-7,8-dihydro-6H-quinoline-3-carbonitrile —— C27H26N2O4
    (7S)-7-(3,4-dimethoxyphenyl)-2,5-dioxo-1-(2,4,6-trimethylphenyl)-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(4-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C23H18N2O2
    (7S)-1-(4-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-2,5-dioxo-7-phenyl-1-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-6H-quinoline-3-carbonitrile —— C23H15F3N2O3
    (7S)-2,5-dioxo-7-phenyl-1-[4-(trifluoromethoxy)phenyl]-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(3-fluorophenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C22H15FN2O2
    (7S)-1-(3-fluorophenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-7-(3-chlorophenyl)-N-(3-fluorophenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C27H23ClFN3OS
    (7R)-7-(3-chlorophenyl)-N-(3-fluorophenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-1-(4-chlorophenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C20H13ClN2O3
    (7S)-1-(4-chlorophenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(3-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C23H18N2O2
    (7S)-1-(3-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(5-chloro-2-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C23H17ClN2O2
    (7S)-1-(5-chloro-2-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-1-(2,3-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C24H20N2O2
    (7R)-1-(2,3-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-1-(4-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C23H18N2O2
    (7R)-1-(4-methylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-1-(4-ethoxyphenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C22H18N2O4
    (7R)-1-(4-ethoxyphenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-7-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C26H24N2O4
    (7R)-7-(3,4-dimethoxyphenyl)-1-(2,5-dimethylphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-1-(2,4-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C24H20N2O2
    (7R)-1-(2,4-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C22H16N2O5
    (7S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-7-(furan-2-yl)-1-(3-methylphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C21H16N2O3
    (7R)-7-(furan-2-yl)-1-(3-methylphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7R)-N-cyclohexyl-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H36N4OS
    (7R)-N-cyclohexyl-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-N-cyclohexyl-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C29H36N4OS
    (7S)-N-cyclohexyl-7-[4-(dimethylamino)phenyl]-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-(3-chlorophenyl)-N-cyclohexyl-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C27H30ClN3OS
    (7S)-7-(3-chlorophenyl)-N-cyclohexyl-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-(3,4-dimethoxyphenyl)-1-(3-fluorophenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C24H19FN2O4
    (7S)-7-(3,4-dimethoxyphenyl)-1-(3-fluorophenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-1-(2,5-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile —— C24H20N2O2
    (7S)-1-(2,5-dimethylphenyl)-2,5-dioxo-7-phenyl-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— 7-bromo-5-[4-[(3R)-3-methylpiperidin-1-yl]-4-oxobutyl]pyrrolo[1,2-a]quinoxalin-4-one —— C21H24BrN3O2
    7-bromo-5-[4-[(3R)-3-methylpiperidin-1-yl]-4-oxobutyl]pyrrolo[1,2-a]quinoxalin-4-one
    —— (7R)-1-(4-fluorophenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C20H13FN2O3
    (7R)-1-(4-fluorophenyl)-7-(furan-2-yl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— (7S)-7-(3-chlorophenyl)-N-(3-fluorophenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide —— C27H23ClFN3OS
    (7S)-7-(3-chlorophenyl)-N-(3-fluorophenyl)-17-thia-2,8-diazatetracyclo[8.7.0.02,6.011,16]heptadeca-1(10),3,5,11(16)-tetraene-8-carboxamide
    —— (7S)-7-(3,4-dimethoxyphenyl)-1-(2-methoxyphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile —— C25H22N2O5
    (7S)-7-(3,4-dimethoxyphenyl)-1-(2-methoxyphenyl)-2,5-dioxo-7,8-dihydro-6H-quinoline-3-carbonitrile
    —— 7-bromo-5-[4-[(3S)-3-methylpiperidin-1-yl]-4-oxobutyl]pyrrolo[1,2-a]quinoxalin-4-one —— C21H24BrN3O2
    7-bromo-5-[4-[(3S)-3-methylpiperidin-1-yl]-4-oxobutyl]pyrrolo[1,2-a]quinoxalin-4-one
    —— 7-[(4-chlorophenyl)methyl]-3-methyl-8-[(2Z)-2-[(E)-4-phenylbut-3-en-2-ylidene]hydrazinyl]purine-2,6-dione —— C23H21ClN6O2
    7-[(4-chlorophenyl)methyl]-3-methyl-8-[(2Z)-2-[(E)-4-phenylbut-3-en-2-ylidene]hydrazinyl]purine-2,6-dione
    —— (7S)-7-(4-chlorophenyl)-N-(4-fluorophenyl)-5-methyl-2-methylsulfanyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide —— C20H17ClFN5OS
    (7S)-7-(4-chlorophenyl)-N-(4-fluorophenyl)-5-methyl-2-methylsulfanyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide
    —— 7-[4-[(2R)-2-ethylpiperidine-1-carbonyl]piperidin-1-yl]sulfonyl-6-methyl-4H-1,4-benzoxazin-3-one —— C22H31N3O5S
    7-[4-[(2R)-2-ethylpiperidine-1-carbonyl]piperidin-1-yl]sulfonyl-6-methyl-4H-1,4-benzoxazin-3-one
    —— 7-[4-[(2S)-2-ethylpiperidine-1-carbonyl]piperidin-1-yl]sulfonyl-6-methyl-4H-1,4-benzoxazin-3-one —— C22H31N3O5S
    7-[4-[(2S)-2-ethylpiperidine-1-carbonyl]piperidin-1-yl]sulfonyl-6-methyl-4H-1,4-benzoxazin-3-one
    —— 7-methoxy-4-methyl-N-[(Z)-quinolin-4-ylmethylideneamino]quinolin-2-amine —— C21H18N4O
    7-methoxy-4-methyl-N-[(Z)-quinolin-4-ylmethylideneamino]quinolin-2-amine
    —— (7S)-7-thiophen-2-yl-16-thia-2,8-diazatetracyclo[8.6.0.02,6.011,15]hexadeca-1(10),3,5,11(15)-tetraene —— C17H16N2S2
    (7S)-7-thiophen-2-yl-16-thia-2,8-diazatetracyclo[8.6.0.02,6.011,15]hexadeca-1(10),3,5,11(15)-tetraene
    —— (7S)-7-phenyl-16-thia-2,8-diazatetracyclo[8.6.0.02,6.011,15]hexadeca-1(10),3,5,11(15)-tetraene —— C19H18N2S
    (7S)-7-phenyl-16-thia-2,8-diazatetracyclo[8.6.0.02,6.011,15]hexadeca-1(10),3,5,11(15)-tetraene