Acetic acid 2-(2-methoxy-propyl)-5,5-dimethyl-3-oxo-cyclohex-1-enyl ester | 122598-33-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Acetic acid 2-(2-methoxy-propyl)-5,5-dimethyl-3-oxo-cyclohex-1-enyl ester
• CAS: 122598-33-8
• 化学式: C₁₄H₂₂O₄
• 分子量: 254.326
• InChiKey: IHVANIQUVCOJEF-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-碘代丙烷 、 乙酸酐 、 2-(2-Methoxy-propyl)-5,5-dimethyl-cyclohexane-1,3-dione 生成 Acetic acid 2-(2-methoxy-propyl)-5,5-dimethyl-3-oxo-cyclohex-1-enyl ester 、 Acetic acid 4-isopropyl-2-(2-methoxy-propyl)-5,5-dimethyl-3-oxo-cyclohex-1-enyl ester 、 Acetic acid 6-isopropyl-2-(2-methoxy-propyl)-5,5-dimethyl-3-oxo-cyclohex-1-enyl ester
  参考文献：
  名称：

  Efficient Regioselective Preparation of 2,6-Disubstituted Derivatives of 3-Acetoxy-5,5-dimethyl-2-cyclohexenone

  摘要：

  Low temperature generation of dianions of 2-alkylated derivatives of dimedone, followed by alkylation at C-4 and quenching of the reaction mixture with acetic anhydride at room temperature furnishes the least sterically hindered 2,6-dialkyl-3-acetoxy-5,5-dimethyl-2-cyclohexenones 2 with high selectivity in a one-pot process.

  DOI：

  10.1055/s-1988-27773