2-amino-6-ethyl-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-7-O-(β-D-tetraacetylglucopyranosyl)-4H-chromen-4-one | 1210915-35-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-amino-6-ethyl-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-7-O-(β-D-tetraacetylglucopyranosyl)-4H-chromen-4-one
• CAS: 1210915-35-7
• 化学式: C₃₃H₃₄N₄O₁₂
• 分子量: 678.653
• InChiKey: DDNAWMOISHPNQG-ZOSYSNNKSA-N

反应信息

• 作为反应物：
  描述：

  2-amino-6-ethyl-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-7-O-(β-D-tetraacetylglucopyranosyl)-4H-chromen-4-one 在 甲醇 、 sodium methylate 作用下， 反应 72.0h， 生成 2-amino-6-ethyl-7-O-(β-D-glucopyranosyl)-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-4H-chromen-4-one
  参考文献：
  名称：

  Highly efficient glucosylation of flavonoids

  摘要：

  A highly efficient procedure for glucosylation of flavonoids by acetobromoglucose is described. Glucosylation is carried out in a two-phase system CHCl3/H2O over 96 h using tetrabutylammonium bromide as phase-transfer catalyst. A purification procedure can be performed without column chromatography, and the yields of the glucosylated flavonoids are mostly quantitative. Acetylated glucosides were deprotected with sodium methanolate to afford the desired glucosides of flavonoids.

  DOI：

  10.1007/s00706-009-0207-6
• 作为产物：
  描述：

  2-amino-6-ethyl-7-hydroxy-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-4H-chromen-4-one 、 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 在 potassium carbonate 、 四丁基溴化铵 作用下， 以 水 、 氯仿 为溶剂， 反应 96.0h， 以92.3%的产率得到2-amino-6-ethyl-3-(4-phenyl-4H-1,2,4-triazol-3-yl)-7-O-(β-D-tetraacetylglucopyranosyl)-4H-chromen-4-one
  参考文献：
  名称：

  Highly efficient glucosylation of flavonoids

  摘要：

  A highly efficient procedure for glucosylation of flavonoids by acetobromoglucose is described. Glucosylation is carried out in a two-phase system CHCl3/H2O over 96 h using tetrabutylammonium bromide as phase-transfer catalyst. A purification procedure can be performed without column chromatography, and the yields of the glucosylated flavonoids are mostly quantitative. Acetylated glucosides were deprotected with sodium methanolate to afford the desired glucosides of flavonoids.

  DOI：

  10.1007/s00706-009-0207-6