(Z)-(4R,5R)-1-n-butylamino-5-hydroxy-4,6-dimethoxy-hex-1-en-3-one | 1187451-94-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (Z)-(4R,5R)-1-n-butylamino-5-hydroxy-4,6-dimethoxy-hex-1-en-3-one
• CAS: 1187451-94-0
• 化学式: C₁₂H₂₃NO₄
• 分子量: 245.319
• InChiKey: CBEXWOPTJVSVBH-YYYFKNSJSA-N

反应信息

• 作为反应物：
  描述：

  (Z)-(4R,5R)-1-n-butylamino-5-hydroxy-4,6-dimethoxy-hex-1-en-3-one 在 5%-palladium/activated carbon 、 氢气 作用下， 以 甲醇 为溶剂， 反应 4.0h， 以92%的产率得到(4R,5R)-5-hydroxy-4,6-dimethoxy-hexan-3-one
  参考文献：
  名称：

  Hydrodeamination of β-enamino ketones to 1,2-dideoxy-d-threo-3-hexulose via palladium

  摘要：

  beta-Enamino ketones Were Successfully synthesized in good to excellent yields by reaction of hex-1-en-3-uloses with amines. After hydrogenation on palladium catalyst, beta-enamino ketones effectively underwent hydrodeamination and were converted to the corresponding 1,2-dideoxy-D-threo-3-hexulose derivatives in 89-95% yields. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.112
• 作为产物：
  描述：

  (2R,3R)-3-methoxy-2-(methoxymethyl)-2,3-dihydro-4H-pyran-4-one 、 正丁胺 以 甲醇 为溶剂， 反应 2.0h， 以97%的产率得到(Z)-(4R,5R)-1-n-butylamino-5-hydroxy-4,6-dimethoxy-hex-1-en-3-one
  参考文献：
  名称：

  Hydrodeamination of β-enamino ketones to 1,2-dideoxy-d-threo-3-hexulose via palladium

  摘要：

  beta-Enamino ketones Were Successfully synthesized in good to excellent yields by reaction of hex-1-en-3-uloses with amines. After hydrogenation on palladium catalyst, beta-enamino ketones effectively underwent hydrodeamination and were converted to the corresponding 1,2-dideoxy-D-threo-3-hexulose derivatives in 89-95% yields. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.06.112