bis(N-D-arabinoseimineanthranilate)Co(II) | 1377522-53-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: bis(N-D-arabinoseimineanthranilate)Co(II)
• CAS: 1377522-53-6
• 化学式: C₂₄H₂₈CoN₂O₁₂
• 分子量: 595.486
• InChiKey: NBPLSFKIONPYEC-PPLXZCPISA-L

反应信息

• 作为产物：
  描述：

  cobalt(II) nitrate hexahydrate 、 N-L-arabitol-1-yliden-anthranilic acid 以 乙醇 为溶剂， 反应 0.25h， 生成 bis(N-D-arabinoseimineanthranilate)Co(II)
  参考文献：
  名称：

  Anti-inflammatory and selective COX-2 inhibitory activities of metal complexes of Schiff bases derived from aldoses

  摘要：

  Mn(II)-, Fe(II)-, Co(II)-, Ni(II)-, and Zn(II)-Schiff base complexes containing anthranilic acid and aldoses as part of the base were prepared and characterized by microanalytical, thermogravimetric, and spectroscopic data. The complexes were found to be four-coordinate, anhydrous, and ML2 type. The spectral and magnetic data indicate a tetrahedral geometry for Mn(II) and Fe(II) complexes, and a planar geometry for Co(II), Ni(II), and Zn(II) complexes. Mn(II) and Zn(II) complexes showed a significant anti-inflammatory activity against kaolin-paw-edema. All the complexes exhibited selective inhibition of COX-2 in two different cell models.

  DOI：

  10.1007/s00044-012-0068-0