7,7-dimethyl-5-oxo-4-phenyl-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile | 1339872-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 7,7-dimethyl-5-oxo-4-phenyl-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile
• CAS: 1339872-95-5
• 化学式: C₂₁H₂₀N₂OS
• 分子量: 348.469
• InChiKey: BOFDFDNPNCXFJY-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  7,7-dimethyl-5-oxo-4-phenyl-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile 以 乙醇 为溶剂， 反应 5.0h， 以80%的产率得到3-allenyl-7,7-dimethyl-5-oxo-4-phenyl-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carbonitrile
  参考文献：
  名称：

  Synthesis and structure of 3-allenyl-4-aryl-7,7-dimethyl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carbonitriles

  摘要：

  3-Allenyl-4-aryl-7,7-dimethyl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carbonitriles were synthesized via [3,3]-sigmatropic rearrangement of 4-aryl-7,7-dimethyl-5-oxo-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitriles. The structure of 3-allenyl-7,7-dimethyl-4-(2-nitrophenyl)-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinolin-3-carbonitrile was determined by X-ray analysis.

  DOI：

  10.1134/s1070428011090144
• 作为产物：
  描述：

  morpholinium 3-cyano-7,7-dimethyl-5-oxo-4-phenyl-1,4,5,6,7,8-hexahydroquinoline-2-thiolate 、 3-溴丙炔 以 乙醇 为溶剂， 反应 3.0h， 以65%的产率得到7,7-dimethyl-5-oxo-4-phenyl-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile
  参考文献：
  名称：

  Synthesis and structure of 3-allenyl-4-aryl-7,7-dimethyl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carbonitriles

  摘要：

  3-Allenyl-4-aryl-7,7-dimethyl-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinoline-3-carbonitriles were synthesized via [3,3]-sigmatropic rearrangement of 4-aryl-7,7-dimethyl-5-oxo-2-(prop-2-yn-1-ylsulfanyl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitriles. The structure of 3-allenyl-7,7-dimethyl-4-(2-nitrophenyl)-5-oxo-2-thioxo-1,2,3,4,5,6,7,8-octahydroquinolin-3-carbonitrile was determined by X-ray analysis.

  DOI：

  10.1134/s1070428011090144