| 1456863-78-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1456863-78-7
• 化学式: C₂₆H₃₂O₂Si
• 分子量: 404.624
• InChiKey: UXEFZFBTWOLPJN-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 Jones reagent 作用下， 以 丙酮 为溶剂， 反应 1.0h， 以80%的产率得到
  参考文献：
  名称：

  A general, flexible, ring closing metathesis (RCM) based strategy for accessing the fused furo[3,2-b]furanone moiety present in diverse bioactive natural products

  摘要：

  A simple and straightforward methodology of general utility to construct sterically encumbered furo[3,2-b]furanone scaffolds present in a diverse range of bioactive natural products is delineated. The methodology emanates from readily available Morita-Baylis-Hillman adducts and employs sequential ring closing metathesis and oxy-Michael addition cascade as the key steps. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.08.021
• 作为产物：
  描述：

  在 Grubbs catalyst first generation 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以93%的产率得到
  参考文献：
  名称：

  A general, flexible, ring closing metathesis (RCM) based strategy for accessing the fused furo[3,2-b]furanone moiety present in diverse bioactive natural products

  摘要：

  A simple and straightforward methodology of general utility to construct sterically encumbered furo[3,2-b]furanone scaffolds present in a diverse range of bioactive natural products is delineated. The methodology emanates from readily available Morita-Baylis-Hillman adducts and employs sequential ring closing metathesis and oxy-Michael addition cascade as the key steps. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.08.021