methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-levulinoyl-β-D-galactopyranosyl-(1->4)-O-{4-methoxyphenyl 2,3-di-O-(4-methylbenzoyl)-β-D-glucopyranosid}uronate | 204525-01-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-levulinoyl-β-D-galactopyranosyl-(1->4)-O-{4-methoxyphenyl 2,3-di-O-(4-methylbenzoyl)-β-D-glucopyranosid}uronate
• CAS: 204525-01-9
• 化学式: C₅₀H₅₃NO₁₇
• 分子量: 939.967
• InChiKey: LDQMSEZMLBUCKI-MKMGZIHDSA-N

反应信息

• 作为反应物：
  描述：

  methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-levulinoyl-β-D-galactopyranosyl-(1->4)-O-{4-methoxyphenyl 2,3-di-O-(4-methylbenzoyl)-β-D-glucopyranosid}uronate 在 camphor-10-sulfonic acid 作用下， 以 甲醇 、 二氯甲烷 为溶剂， 反应 120.0h， 以54%的产率得到methyl 2-acetamido-2-deoxy-3-O-levulinoyl-β-D-galactopyranosyl-(1->4)-O-{4-methoxyphenyl 2,3-di-O-(4-methylbenzoyl)-β-D-glucopyranosid}uronate
  参考文献：
  名称：

  Synthesis of chondroitin sulfate E octasaccharide in a repeating region involving an acetamide auxiliary

  摘要：

  Chondroitin sulfate E repeating octasaccharide was effectively synthesized in a stereocontrolled manner by adopting an acetamide-type disaccharide unit. In the tetrasaccharide synthesis we isolated a characteristic glycosyl imidate as a reactive intermediate. An acetamide auxiliary involves the glycosylation mechanism. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.09.009
• 作为产物：
  描述：

  、 乙酸酐 在 吡啶 作用下， 反应 2.0h， 生成 methyl 2-acetamido-4,6-O-benzylidene-2-deoxy-3-O-levulinoyl-β-D-galactopyranosyl-(1->4)-O-{4-methoxyphenyl 2,3-di-O-(4-methylbenzoyl)-β-D-glucopyranosid}uronate
  参考文献：
  名称：

  Synthesis of chondroitin sulfate E octasaccharide in a repeating region involving an acetamide auxiliary

  摘要：

  Chondroitin sulfate E repeating octasaccharide was effectively synthesized in a stereocontrolled manner by adopting an acetamide-type disaccharide unit. In the tetrasaccharide synthesis we isolated a characteristic glycosyl imidate as a reactive intermediate. An acetamide auxiliary involves the glycosylation mechanism. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.carres.2007.09.009