(4-hydroxy-3-methoxyphenyl)(5-(4-hydroxy-3-methoxyphenyl)-1H-imidazol-2-yl)methanone | 1426148-07-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4-hydroxy-3-methoxyphenyl)(5-(4-hydroxy-3-methoxyphenyl)-1H-imidazol-2-yl)methanone
• CAS: 1426148-07-3
• 化学式: C₁₈H₁₆N₂O₅
• 分子量: 340.335
• InChiKey: QOIBAJYHBBMWLG-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-Azido-1-(4-hydroxy-3-methoxyphenyl)ethanone 在 potassium ethyl xanthogenate 作用下， 以 异丙醇 为溶剂， 反应 6.0h， 生成 (4-hydroxy-3-methoxyphenyl)(5-(4-hydroxy-3-methoxyphenyl)-1H-imidazol-2-yl)methanone 、 (4-hydroxy-3-methoxyphenyl)(4-(4-hydroxy-3-methoxyphenyl)-1H-imidazol-2-yl)methanone
  参考文献：
  名称：

  One-pot synthesis of disubstituted imidazole derivatives from α-azido ketones catalyzed by potassium ethylxanthate

  摘要：

  An efficient, novel procedure for the synthesis of new imidazole derivatives from alpha-azido ketones is described. This reaction proceeds via dimerization of aryl glyoxal imino generated from alpha-azido ketones in the presence of potassium ethylxanthate as a catalyst. A possible mechanism for the entire sequence is proposed. (c) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.01.042