3t-(8-ethoxy-[2]quinolyl)-acrylic acid ethyl ester | 93009-19-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 3t-(8-ethoxy-[2]quinolyl)-acrylic acid ethyl ester
• 英文别名: 3t-(8-Aethoxy-[2]chinolyl)-acrylsaeure-aethylester
• CAS: 93009-19-9
• 化学式: C₁₆H₁₇NO₃
• 分子量: 271.316
• InChiKey: PJJWGTQNTFKTQF-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.21
• 重原子数：
  20.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  48.42
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  3t-(8-ethoxy-[2]quinolyl)-acrylic acid 在 盐酸 、 乙醇 作用下， 生成 3t-(8-ethoxy-[2]quinolyl)-acrylic acid ethyl ester
  参考文献：
  名称：

  Donor finger morbidity in cross-finger flaps

  摘要：

  We reviewed 16 patients who had cross-finger flap procedures carried out between 1991 and 1996 at the West Midlands Regional centre for Plastic and Reconstructive Surgery. We looked specifically at the donor finger morbidity of each patient with a median follow up interval of 43 months.At follow up there were 10 patients with cold intolerance, eight patients with subjective joint stiffness and a documented reduced range of finger joint movement. Skin graft reconstruction of the secondary defect was associated with poor colour match in eight cases (seven hyperpigmented, one hypopigmented) and visible contour deformity in eight cases. There were no clinically significant differences between split skin graft or full thickness skin graft for donor finger reconstruction.Although cross-finger flaps may provide soft tissue cover in a variety of finger pulp injuries, these results show an alarming incidence of donor finger morbidity associated with such procedures. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0020-1383(99)00205-3