3,7-bis(4-nitrophenyl)-15-(triisopropylsilylethynyl)-10,20-bis(3,5-di-tert-butylphenyl)porphyrin Ni(II) | 1573176-65-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 3,7-bis(4-nitrophenyl)-15-(triisopropylsilylethynyl)-10,20-bis(3,5-di-tert-butylphenyl)porphyrin Ni(II)
• CAS: 1573176-65-4
• 化学式: C₇₁H₇₈N₆NiO₄Si
• 分子量: 1166.21
• InChiKey: XFZXKRJWMKUXIC-NZBZUGNFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  3,7-bis(4-nitrophenyl)-15-(triisopropylsilylethynyl)-10,20-bis(3,5-di-tert-butylphenyl)porphyrin Ni(II) 在 四丁基氟化铵 、 4-十二烷基苯磺酸 作用下， 以 四氢呋喃 、 水 、 1,2-二氯乙烷 为溶剂， 反应 24.17h， 以53%的产率得到3,7-bis(4-nitrophenyl)-10,20-bis(3,5-di-tert-butylphenyl)porphyrin Ni(II)
  参考文献：
  名称：

  Silylethynyl Substituents as Porphyrin Protecting Groups for Solubilization and Selectivity Control

  摘要：

  Silylethynyl substituents are proposed as protecting groups for porphyrin derivatives to enhance their solubility and enable regioselective functionalization. After usage as protecting groups, silylethynyl groups at the mesa-positions can be efficiently removed upon heating with aqueous H2SO4 in the presence of a surfactant. This approach was applied to the preparation of unsymmetrically beta-substituted porphyrins and porphin-porphyrin oligomers, which were inaccessible by conventional methods.

  DOI：

  10.1021/ol500569b
• 作为产物：
  描述：

  、 1-溴-4-硝基苯 在 2-双环己基膦-2',6'-二甲氧基联苯 、 tris(dibenzylideneacetone)dipalladium(0) chloroform complex 、 caesium carbonate 作用下， 以 水 、 N,N-二甲基甲酰胺 、 甲苯 为溶剂， 反应 5.0h， 以17.1 mg的产率得到3,7-bis(4-nitrophenyl)-15-(triisopropylsilylethynyl)-10,20-bis(3,5-di-tert-butylphenyl)porphyrin Ni(II)
  参考文献：
  名称：

  Silylethynyl Substituents as Porphyrin Protecting Groups for Solubilization and Selectivity Control

  摘要：

  Silylethynyl substituents are proposed as protecting groups for porphyrin derivatives to enhance their solubility and enable regioselective functionalization. After usage as protecting groups, silylethynyl groups at the mesa-positions can be efficiently removed upon heating with aqueous H2SO4 in the presence of a surfactant. This approach was applied to the preparation of unsymmetrically beta-substituted porphyrins and porphin-porphyrin oligomers, which were inaccessible by conventional methods.

  DOI：

  10.1021/ol500569b