| 1023282-07-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1023282-07-6
• 化学式: C₁₂H₁₆IN₃O₇
• 分子量: 441.179
• InChiKey: XIHWXJHDEHLKHA-SCWFEDMQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.25
• 重原子数：
  23.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  136.89
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  、 uridine diphosphate bis(tetrabutylammonium) salt 以4%的产率得到
  参考文献：
  名称：

  6-Azido d-galactose transfer to N-acetyl-d-glucosamine derivative using commercially available β-1,4-galactosyltransferase

  摘要：

  A new strategy to tag glycoproteins carrying terminal GlcNAc was developed using commercially available bovine beta-1,4-galactosyltransferase (Ga1T) and UDP-6-azidogalactose. The azide function was then allowed to react via a biotinylated Staudinger-Bertozzi probe demonstrating the usefulness of such a procedure to tag any glycoprotein possessing a N-acetylglucosamine terminal residue from any type of cell lysate. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.02.018
• 作为产物：
  描述：

  1,2,3,4-四-O-乙酰基-6-叠氮基-6-脱氧Α-D吡喃半乳糖 在 bismuth(III) iodide 、 碘代三甲硅烷 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  6-Azido d-galactose transfer to N-acetyl-d-glucosamine derivative using commercially available β-1,4-galactosyltransferase

  摘要：

  A new strategy to tag glycoproteins carrying terminal GlcNAc was developed using commercially available bovine beta-1,4-galactosyltransferase (Ga1T) and UDP-6-azidogalactose. The azide function was then allowed to react via a biotinylated Staudinger-Bertozzi probe demonstrating the usefulness of such a procedure to tag any glycoprotein possessing a N-acetylglucosamine terminal residue from any type of cell lysate. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.02.018