((E)-1-But-3-enyl-1-hexa-1,5-diynyl-dec-8-en-4-ynyloxy)-tert-butyl-dimethyl-silane | 208249-56-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: ((E)-1-But-3-enyl-1-hexa-1,5-diynyl-dec-8-en-4-ynyloxy)-tert-butyl-dimethyl-silane
• 英文别名: 7-but-3-enylhexadec-14-en-1,5,10-triyn-7-yloxy-tert-butyl-dimethylsilane
• CAS: 208249-56-3
• 化学式: C₂₆H₄₀OSi
• 分子量: 396.689
• InChiKey: AOZCJJXVKDASBS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.27
• 重原子数：
  28
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ((E)-1-But-3-enyl-1-hexa-1,5-diynyl-dec-8-en-4-ynyloxy)-tert-butyl-dimethyl-silane 在 Grubbs catalyst first generation 作用下， 以 苯 为溶剂， 反应 4.0h， 以70%的产率得到tert-Butyl-dimethyl-(1,2,6,7,11,12,16,17-octahydro-cyclopenta[a]phenanthren-13-yloxy)-silane
  参考文献：
  名称：

  Ruthenium-Catalyzed Polycyclization Reactions

  摘要：

  The application of ruthenium alkylidenes such as 1 to the catalysis of polycyclization reactions is reported. Several acyclic precursors have been synthesized and reacted with 1. These precursors vary in topology and contain acetylenic and/or cycloolefinic metathesis relays. The cyclization reactions proceed in moderate to good yields to produce polycyclic polyenes when the precursors are subjected to catalytic amounts of 1. In general, precursors bearing n relay units generate polycycles containing (n + 1) rings.

  DOI：

  10.1021/jo972279g
• 作为产物：
  描述：

  1,5-己二炔 在 正丁基锂 、 三乙胺 作用下， 以 四氢呋喃 、 二氯甲烷 为溶剂， 生成 ((E)-1-But-3-enyl-1-hexa-1,5-diynyl-dec-8-en-4-ynyloxy)-tert-butyl-dimethyl-silane
  参考文献：
  名称：

  Ruthenium-Catalyzed Polycyclization Reactions

  摘要：

  The application of ruthenium alkylidenes such as 1 to the catalysis of polycyclization reactions is reported. Several acyclic precursors have been synthesized and reacted with 1. These precursors vary in topology and contain acetylenic and/or cycloolefinic metathesis relays. The cyclization reactions proceed in moderate to good yields to produce polycyclic polyenes when the precursors are subjected to catalytic amounts of 1. In general, precursors bearing n relay units generate polycycles containing (n + 1) rings.

  DOI：

  10.1021/jo972279g